Human Cathepsin L ELISA Kit PicoKine® | Boster EK0676 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human Cathepsin L ELISA Kit PicoKine®

catalog :

EK0676

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK0676

Product Name :

Human Cathepsin L ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human Cathepsin L ELISA Kit PicoKine® (96 Tests). Quantitate Human CTSL in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

CTSL

Uniprot ID :

P07711

Immunogen :

Expression system for standard: NS0; Immunogen sequence: E113-V333

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

62.5 pg/ml - 4,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Cathepsin L1

Synonyms :

Cathepsin L1;3.4.22.15;Cathepsin L;Major excreted protein;MEP;Cathepsin L1 heavy chain;Cathepsin L1 light chain;CTSL;CTSL1;

Protein Name :

Cathepsin L1

Molecular Weight :

37564 MW

Protein Function :

Important for the overall degradation of proteins in lysosomes.

Subcellular Localization :

Lysosome

Background :

Cathepsin L is an important lysosomal endopeptidase enzyme which is involved in the initiation of protein degradation. It also shows the most potent collagenolytic and elastinolytic activity in vitro of any of the cathepsins. The gene is mapped to 9q21-q22. It is a member of the Peptidase C1 family, which play an important role in diverse processes including normal lysosome mediated protein turnover, antigen and proprotein processing, and apoptosis. Cathepsin L has been reported in many organisms including fish, birds and mammals.

Research Category :

Cell Adhesion Proteins, Cytoskeleton / Ecm, Ecm Enzymes, Extracellular Matrix, Membrane Proteins, Neuroscience, Signal Transduction