Mouse Cathepsin D ELISA Kit PicoKine® | Boster EK0673 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse Cathepsin D ELISA Kit PicoKine®

catalog :

EK0673

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK0673

Product Name :

Mouse Cathepsin D ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Mouse Cathepsin D ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Ctsd in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Mouse

Application :

ELISA

Gene Name :

CTSD

Uniprot ID :

Q3UCD9

Immunogen :

Expression system for standard: NS0; Immunogen sequence: I21-L410

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

312 pg/ml - 20,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

polyclonal antibody from goat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Cathepsin D

Synonyms :

Cathepsin D;3.4.23.5;Ctsd;

Protein Name :

Cathepsin D

Molecular Weight :

44954 MW

Protein Function :

Acid protease active in intracellular protein breakdown.

Subcellular Localization :

Lysosome. Melanosome . Secreted, extracellular space .

Background :

Cathepsin D is a protein that in humans is encoded by the CTSD gene. This proteinase is a member of the peptidase C1 family, having a specificity similar to but narrower than that of pepsin A. It is mapped to 11p15.5. The cDNA encodes a 412-amino acid protein with 20 and 44 amino acids in a pre- and prosegment, respectively. Cathepsin D is one of the lysosomal proteinases. It is ubiquitously expressed and is involved in proteolytic degradation, cell invasion, and apoptosis. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease and it has been considered as a breast cancer tumor marker.

Research Category :

Cancer, Cell Adhesion Proteins, Cell Biology, Cytoskeleton / Ecm, Ecm Enzymes, Extracellular Matrix, Invasion/Microenvironment, Membrane Proteins, Neuroscience, Proteolysis / Ubiquitin, Proteolytic Enzymes, Signal Transduction