Mouse P-Cadherin-3 Cdh3 ELISA Kit PicoKine® | Boster EK0668 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse P-Cadherin-3 Cdh3 ELISA Kit PicoKine®

catalog :

EK0668

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK0668

Product Name :

Mouse P-Cadherin-3 Cdh3 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Mouse P-Cadherin-3 Cdh3 ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Cdh3 in cell culture supernatants and serum. Sensitivity: 10pg/ml.

Reactivity :

Mouse

Application :

ELISA

Gene Name :

CDH3

Uniprot ID :

P10287

Immunogen :

Expression system for standard: NS0; Immunogen sequence: E100-G647

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

62.5 pg/ml - 4,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants and serum

Capture/Detection Antibodies :

monoclonal antibody from rat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Cadherin-3

Synonyms :

Cadherin-3;Placental cadherin;P-cadherin;Cdh3;Cdhp;

Protein Name :

Cadherin-3

Molecular Weight :

90612 MW

Protein Function :

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.

Subcellular Localization :

Cell membrane; Single-pass type I membrane protein.

Background :

P-Cadherin, also known as Cadherin-3 (CDH3), is a protein that in humans is encoded by the CDH3 gene. This gene is a classical cadherin from the cadherin superfamily. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy. Cells expressing CDH3 also adhered to one another more tightly than the parental cell line.

Research Category :

Cadherins, Cell Adhesion, Cytoskeleton / Ecm, Neuroscience, Sensory System, Signal Transduction, Visual System