Human P-Cadherin-3 CDH3 ELISA Kit PicoKine® | Boster EK0667 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human P-Cadherin-3 CDH3 ELISA Kit PicoKine®

catalog :

EK0667

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK0667

Product Name :

Human P-Cadherin-3 CDH3 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human P-Cadherin-3 CDH3 ELISA Kit PicoKine® (96 Tests). Quantitate Human CDH3 in cell culture supernatants and serum. Sensitivity: 2pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

CDH3

Uniprot ID :

P22223

Immunogen :

Expression system for standard: NS0; Immunogen sequence: D108-G654

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

62.5 pg/ml - 4,000 pg/ml

Sensitivity :

<2 pg/ml

Sample Type :

cell culture supernatants and serum

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Cadherin-3

Synonyms :

Cadherin-3;Placental cadherin;P-cadherin;CDH3;CDHP;

Protein Name :

Cadherin-3

Molecular Weight :

91418 MW

Protein Function :

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.

Subcellular Localization :

Cell membrane; Single-pass type I membrane protein.

Tissue Specificity :

Expressed in some normal epithelial tissues and in some carcinoma cell lines.

Sequence Similarities :

Contains 5 cadherin domains.

Background :

Cadherins are calcium-dependent cell-cell adhesion molecules that mediate cell-cell binding in a homophilic manner. They play an important role in the growth and development of cells via the mechanisms of control of tissue architecture and the maintenance of tissue integrity. Cadherin expression is regulated spatially as well as temporally. Cadherins are thought to play an important role in development and maintenance of tissues through selective cell-cell adhesion activity and may be involved also in the invasion and metastasis of malignant tumors. Cadherin regulates dendritic spine morphogenesis. A cadherin gene cluster is mapped to a region of chromosome 5 subject to frequent allelic loss in carcinoma. The standard product used in this kit is recombinant P-Cadherin with the molecular mass of 120-130Kda after glycosylation.

Research Category :

Cadherins, Cell Adhesion, Cytoskeleton / Ecm, Neuroscience, Sensory System, Signal Transduction, Visual System