Human ADAM8/Ms2 ELISA Kit PicoKine® | Boster EK0650 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human ADAM8/Ms2 ELISA Kit PicoKine®

catalog :

EK0650

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK0650

Product Name :

Human ADAM8/Ms2 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human ADAM8/Ms2 ELISA Kit PicoKine® (96 Tests). Quantitate Human ADAM8 in cell culture supernatants and serum. Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

ADAM8

Uniprot ID :

P78325

Immunogen :

Expression system for standard: NS0; Immunogen sequence: M1-P497

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

62.5 pg/ml - 4,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants and serum

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Disintegrin and metalloproteinase domain-containing protein 8

Synonyms :

Disintegrin and metalloproteinase domain-containing protein 8;ADAM 8;3.4.24.-;Cell surface antigen MS2;CD156a;ADAM8;MS2;

Protein Name :

Disintegrin and metalloproteinase domain-containing protein 8

Molecular Weight :

88771 MW

Protein Function :

Possible involvement in extravasation of leukocytes.

Subcellular Localization :

Membrane; Single-pass type I membrane protein.

Tissue Specificity :

Expressed on neutrophils and monocytes.

Background :

A Disintegrin and metalloproteinase domain-containing protein 8 is an enzyme that in humans is encoded by the ADAM8 gene. ADAM8 is localized to chromosome 10q26.3. This gene encodes a member of the ADAM (a disintegrin and metalloproteinase domain) family. Members of the ADAM family, such as ADAM8, are cell surface proteases involved in remodeling of extracellular matrix, cell migration, and processing of membrane-bound signaling molecules. They are characterized by disintegrin and metalloprotease domains that confer adhesive properties and proteolytic activities, respectively. And the protein encoded by this gene may be involved in cell adhesion duringneurodegeneration.

Research Category :

Apoptosis, Cancer, Cell Biology, Cell Death, Cytoskeleton / Ecm, Ecm Enzymes, Extracellular Matrix, Invasion/Microenvironment, Metalloprotease, Proteolysis / Ubiquitin, Proteolytic Enzymes, Receptors, Signal Transduction