Mouse Adiponectin ELISA Kit PicoKine® | Boster EK0596 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse Adiponectin ELISA Kit PicoKine®

catalog :

EK0596

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK0596

Product Name :

Mouse Adiponectin ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Mouse Adiponectin ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Adipoq in cell culture supernatants, serum, plasma (heparin, EDTA) and urine. Sensitivity: 10pg/ml.

Reactivity :

Mouse

Application :

ELISA

Gene Name :

ADIPOQ

Uniprot ID :

Q60994

Immunogen :

Expression system for standard: NS0; Immunogen sequence: E18-N244

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

312 pg/ml - 20,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, serum, plasma (heparin, EDTA) and urine

Capture/Detection Antibodies :

monoclonal antibody from rat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Adiponectin

Synonyms :

Adiponectin;30 kDa adipocyte complement-related protein;Adipocyte complement-related 30 kDa protein;ACRP30;Adipocyte, C1q and collagen domain-containing protein;Adipocyte-specific protein AdipoQ;Adipoq;Acdc, Acrp30, Apm1;

Protein Name :

Adiponectin

Molecular Weight :

26809 MW

Protein Function :

Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.

Subcellular Localization :

Secreted.

Tissue Specificity :

Synthesized exclusively by adipocytes and secreted into plasma.

Sequence Similarities :

Contains 1 C1q domain.

Background :

Adiponectin (ADPN) is a hormone secreted by adipocytes that regulates energy homeostasis and glucose and lipid metabolism. Adiponectin is a new member of the family of soluble defense collagens, in hematopoiesis and immune responses. It is an important negative regulator in hematopoiesis and immune systems and raise the possibility that it may be involved in ending inflammatory responses through its inhibitory functions. Adiponectin is mapped to 3q27 and can protect the organism from systemic inflammation by promoting the clearance of early apoptotic cells by macrophages through a receptor-dependent pathway involving calreticulin.

Research Category :

Atherosclerosis, Cancer, Cancer Metabolism, Cardiovascular, Diabetes, Diabetes Associated, Growth Factors/Hormones, Heart Disease, Lipids / Lipoproteins, Mesenchymal Stem Cells, Metabolism, Metabolism Processes, Neurology Process, Neuroscience, Obesity, Pathways And Processes, Response To Hypoxia, Signal Transduction, Stem Cells