Mouse CCL24/Eotaxin-2 ELISA Kit PicoKine® | Boster EK0576 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse CCL24/Eotaxin-2 ELISA Kit PicoKine®

catalog :

EK0576

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK0576

Product Name :

Mouse CCL24/Eotaxin-2 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Mouse CCL24/Eotaxin-2 ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Ccl24 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Mouse

Application :

ELISA

Gene Name :

CCL24

Uniprot ID :

Q9JKC0

Immunogen :

Expression system for standard: E.coli; Immunogen sequence: V27-V119

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

15.6 pg/ml - 1,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from rat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

C-C motif chemokine 24

Synonyms :

C-C motif chemokine 24;Eosinophil chemotactic protein 2;Eotaxin-2;Small-inducible cytokine A24;Ccl24;Scya24;

Protein Name :

C-C motif chemokine 24

Molecular Weight :

12871 MW

Protein Function :

Chemotactic for resting T-lymphocytes, and eosinophils. Has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. Binds to CCR3 (By similarity).

Subcellular Localization :

Secreted.

Tissue Specificity :

Highest expression in jejunum and spleen. Lower levels found in liver and lung. No expression detected in kidney, thymus, brain or testis.

Background :

Chemokine (C-C motif) ligand 24 (CCL24) also known as myeloid progenitor inhibitory factor 2 (MPIF-2) or eosinophil chemotactic protein 2 (eotaxin-2) is a protein that in humans is encoded by the CCL24 gene.1 By use of PCR analysis of somatic cell hybrid DNAs, radiation hybrid mapping, and a chromosome 7-specific YAC library, mapped the SCYA24 gene to chromosome 7q11.23.2 CCL24 is a small cytokine belonging to the CC chemokine family. CCL24 interacts with chemokine receptor CCR3 to induce chemotaxis in eosinophils.3 This chemokine is also strongly chemotactic for resting T lymphocytes and slightly chemotactic for neutrophils.

Research Category :

Chemokines, Immunology, Innate Immunity