Mouse MCP-1 ELISA Kit PicoKine® | Boster EK0568 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse MCP-1 ELISA Kit PicoKine®

catalog :

EK0568

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK0568

Product Name :

Mouse MCP-1 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Mouse MCP-1 ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Ccl2 in cell culture supernatants and serum. Sensitivity: 6pg/ml.

Reactivity :

Mouse

Application :

ELISA

Gene Name :

CCL2

Uniprot ID :

P10148

Immunogen :

Expression system for standard: E.coli; Immunogen sequence: Q24-R96

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

15.6 pg/ml - 1,000 pg/ml

Sensitivity :

<6 pg/ml

Sample Type :

cell culture supernatants and serum

Capture/Detection Antibodies :

monoclonal antibody from rat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

C-C motif chemokine 2

Synonyms :

C-C motif chemokine 2;Monocyte chemoattractant protein 1;Monocyte chemotactic protein 1;MCP-1;Platelet-derived growth factor-inducible protein JE;Small-inducible cytokine A2;Ccl2;Je, Mcp1, Scya2;

Protein Name :

C-C motif chemokine 2

Molecular Weight :

16326 MW

Protein Function :

Chemotactic factor that attracts monocytes, but not neutrophils.

Subcellular Localization :

Secreted.

Background :

Monocyte chemotactic protein-1 (MCP-1) is a member of the small inducible gene (SIG) family. It has been shown to play a role in the recruitment of monocytes to sites of injury and infection. By analysis of a panel of somatic cell hybrids, we have localized the MCP-1 gene, designated SCYA2, to human chromosome 17. In situ hybridization confirmed this assignment and further localized the gene to 17q11.2-q21.1. MCP-1 plays a unique and crucial role in the initiation of atherosclerosis and may provide a new therapeutic target in this disorder. Monocyte chemoattractant protein-1 (MCP-1), regulated on activation, normal T cell expressed and secreted,and stimulation of monocytes from healthy carriers of the genotype GG with Mycobacterium tuberculosis antigens yielded higher MCP-1. The standard used in this kit is recombinant mouse MCP-1 (Q24-R96) with the molecular mass of 8.5Kda.

Research Category :

Angiogenesis, Atherosclerosis, Cancer, Cancer Metabolism, Cardiovascular, Chemokines, Heart Disease, Immunology, Innate Immunity, Invasion/Microenvironment, Metabolism, Metabolism Processes, Pathways And Processes, Response To Hypoxia, Vascular Inflammation