Mouse Thrombopoietin/TPO PicoKine ELISA Kit | Boster EK0517 product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse Thrombopoietin/TPO PicoKine ELISA Kit

catalog :

EK0517

quantity :

96 wells/kit

price :

340 USD

more info or order :

Boster product webpage

product information

sku :

EK0517

name :

Mouse Thrombopoietin/TPO PicoKine ELISA Kit

price :

340 USD

immunogen :

Expression system for standard: NSO; Immunogen sequence: S22-T356

description :

Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse TPO

size :

96 wells/kit

reactivity :

Mouse

applications :

ELISA

background :

Thrombopoietin(TPO) is also called megakaryocyte growth and development factor(MGDF). TPO, a lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from committed progenitor cells, is believed to be the major physiological regulator of circulating platelet levels. Human, dog, and mouse cDNAs for MGDF are highly conserved and encode open reading frames for proteins of 353, 352, and 356 amino acids, respectively, including predicted signal peptides. MGDF is a novel cytokine that regulates megakaryocyte development and is a ligand for the MPL receptor. The human MGDF gene has been mapped to chromosome 3q26.3. The standard product used in this kit is gene recombinant mouse TPO, consisting of 335 amino acids with the molecular mass of 35KDa. As a result of glycosylation, the molecular mass is 75KDa.

cross reactivity :

There is no detectable cross-reactivity with other relevant proteins.

gene full name :

Thrombopoietin

gene name :

TPO; Thpo

protein function :

Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.

protein name :

Thrombopoietin

research category :

immunology cell type markers platelets stem cells hematopoietic progenitors myeloid thrombocytic lineage

storage :

Store at 4ËšC for 6 months, at -20ËšC for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

subcellular localization :

Secreted.

synonyms :

Thrombopoietin;C-mpl ligand;ML;Megakaryocyte colony-stimulating factor;Megakaryocyte growth and development factor;MGDF;Myeloproliferative leukemia virus oncogene ligand;Thpo;

tissue specificity :

Found mainly in the liver, kidney and skeletal muscle.

uniprot id :

P40226

more info or order :

Boster product webpage