Human sL-Selectin PicoKine ELISA Kit | Boster EK0503 product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human sL-Selectin PicoKine ELISA Kit

catalog :

EK0503

quantity :

96 wells/kit

price :

350 USD

more info or order :

Boster product webpage

product information

sku :

EK0503

name :

Human sL-Selectin PicoKine ELISA Kit

price :

350 USD

immunogen :

Expression system for standard: NSO; Immunogen sequence: W39-N332

description :

Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human sL-Selectin

size :

96 wells/kit

reactivity :

Human

applications :

ELISA

background :

L-selectin, also known as CD62L, is a cell adhesion molecule found on leukocytes. It belongs to the selectin family of proteins, which recognize sialylated carbohydrate groups. It is cleaved by ADAM17.SELL(L-selectin)is a cell surface component that is a member of a family of adhesion/homing receptors which play important roles in leukocyte-endothelial cell interactions. The molecule is composed of multiple domains: one homologous to lectins, one to epidermal growth factor, and two to the consensus repeat units found in C3/C4 binding proteins.1L-selectin acts as a "homing receptor" for leukocytes to enter secondary lymphoid tissues via high endothelial venules. Ligands present on endothelial cells will bind to leukocyte expressing L-selectin, slowing leukocyte trafficking through the blood, and facilitating entry into a secondary lymphoid organ at that point2.

cross reactivity :

There is no detectable cross-reactivity with other relevant proteins.

gene full name :

L-selectin

gene name :

SELL

protein function :

Cell surface adhesion protein. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia.

protein name :

L-selectin

research category :

cardiovascular blood immunology adaptive immunity t cells stem cells hematopoietic progenitors lymphoid t lymphocytic lineage myeloid neutrophil lineage regulatory t cells

sequence similarities :

Belongs to the selectin/LECAM family.

storage :

Store at 4ËšC for 6 months, at -20ËšC for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

subcellular localization :

Membrane; Single-pass type I membrane protein.

synonyms :

L-selectin;CD62 antigen-like family member L;Leukocyte adhesion molecule 1;LAM-1;Leukocyte surface antigen Leu-8;Leukocyte-endothelial cell adhesion molecule 1;LECAM1;Lymph node homing receptor;TQ1;gp90-MEL;CD62L;SELL;LNHR, LYAM1;

tissue specificity :

Expressed in B-cell lines and T-lymphocytes.

uniprot id :

P14151

more info or order :

Boster product webpage