Mouse sE-Selectin ELISA Kit PicoKine® | Boster EK0502 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse sE-Selectin ELISA Kit PicoKine®

catalog :

EK0502

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK0502

Product Name :

Mouse sE-Selectin ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Mouse sE-Selectin ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Sele in cell culture supernatants, serum and plasma (heparin, citrate). Sensitivity: 10pg/ml.

Reactivity :

Mouse

Application :

ELISA

Gene Name :

SELE

Uniprot ID :

Q00690

Immunogen :

Expression system for standard: NS0; Immunogen sequence: W22-P557

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

156 pg/ml - 10,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, serum and plasma (heparin, citrate)

Capture/Detection Antibodies :

monoclonal antibody from rat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

E-selectin

Synonyms :

E-selectin;CD62 antigen-like family member E;Endothelial leukocyte adhesion molecule 1;ELAM-1;Leukocyte-endothelial cell adhesion molecule 2;LECAM2;CD62E;Sele;Elam-1;

Protein Name :

E-selectin

Molecular Weight :

66750 MW

Protein Function :

Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with PSGL1/SELPLG. May have a role in capillary morphogenesis.

Subcellular Localization :

Cell membrane ; Single-pass type I membrane protein.

Sequence Similarities :

Belongs to the selectin/LECAM family.

Background :

E-selectin, also called endothelial-leukocyte adhesion molecule-1 (ELAM-1), is a cell surface glycoprotein expressed by cytokine-activated endothelium that mediates the adhesion of blood neutrophils. An increased expression of E-selectin has been observed in the arterial endothelium interacting with lymphocytes and macrophages in human atherosclerotic lesions. E-selectin plays a critical role in mediating tissue-specific homing of T cells into skin, and of primitive hematopoietic progenitor cells (HPCs) into bone marrow (BM). A structurally and functionally related group of genes, lymph node homing receptor (LHR), granule membrane protein 140 (GMP-140), and endothelial leukocyte adhesion molecule 1 (ELAM-1) are shown to constitute a gene cluster on mouse and human chromosome 1. The standard product used in this kit is recombinant mouse E-Selectin, excluding intercellular E-Selectin and transmembrane domain. It consists of totally 557 amino acids with the molecular mass of 85.8KDa.

Research Category :

Cancer, Cofactors, Vitamins / Minerals, Metabolism, Neurodegenerative Disease, Neurology Process, Neuroscience, Oncoproteins/Suppressors, Pathways And Processes, Signal Transduction, Tumor Suppressors, Vitamins / Minerals