Human sE-Selectin PicoKine ELISA Kit | Boster EK0501 product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human sE-Selectin PicoKine ELISA Kit

catalog :

EK0501

quantity :

96 wells/kit

price :

300 USD

more info or order :

Boster product webpage

product information

sku :

EK0501

name :

Human sE-Selectin PicoKine ELISA Kit

price :

300 USD

immunogen :

Expression system for standard: NSO; Immunogen sequence: W22-P556

description :

Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human sE-Selectin

size :

96 wells/kit

reactivity :

Human

applications :

ELISA

background :

E-selectin, also called endothelial-leukocyte adhesion molecule-1(ELAM-1), is a cell surface glycoprotein expressed by cytokine-activated endothelium that mediates the adhesion of blood neutrophils. An increased expression of E-selectin has been observed in the arterial endothelium interacting with lymphocytes and macrophages in human atherosclerotic lesions. E-selectin plays a critical role in mediating tissue-specific homing of T cells into skin, and of primitive hematopoietic progenitor cells(HPCs) into bone marrow(BM). A structurally and functionally related group of genes, lymph node homing receptor(LHR), granule membrane protein 140(GMP-140), and endothelial leukocyte adhesion molecule 1(ELAM-1) are shown to constitute a gene cluster on mouse and human chromosome 1. The standard product used in this kit is recombinant human E-Selectin, excluding intercellular E-Selectin and transmembrane domain. It consists of totally 535 amino acids with the molecular mass of 58.6KDa.

cross reactivity :

There is no detectable cross-reactivity with other relevant proteins.

gene full name :

E-selectin

gene name :

SELE

protein function :

Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with PSGL1/SELPLG. May have a role in capillary morphogenesis.

protein name :

E-selectin

research category :

neuroscience neurology process neurodegenerative disease signal transduction metabolism vitamins / minerals cancer oncoproteins/suppressors tumor suppressors metabolism pathways and processes cofactors, vitamins / minerals types of disease

sequence similarities :

Belongs to the selectin/LECAM family.

storage :

Store at 4ËšC for 6 months, at -20ËšC for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

subcellular localization :

Cell membrane ; Single-pass type I membrane protein.

synonyms :

E-selectin;CD62 antigen-like family member E;Endothelial leukocyte adhesion molecule 1;ELAM-1;Leukocyte-endothelial cell adhesion molecule 2;LECAM2;CD62E;SELE;ELAM1;

uniprot id :

P16581

more info or order :

Boster product webpage