Rat Rantes ELISA Kit PicoKine® | Boster EK0496 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Rat Rantes ELISA Kit PicoKine®

catalog :

EK0496

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK0496

Product Name :

Rat Rantes ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Rat Rantes ELISA Kit PicoKine® (96 Tests). Quantitate Rat Ccl5 in cell culture supernatants, serum and plasma (heparin, EDTA, citrate). Sensitivity: 1pg/ml.

Reactivity :

Rat

Application :

ELISA

Gene Name :

CCL5

Uniprot ID :

Q6PED1

Immunogen :

Expression system for standard: E.coli; Immunogen sequence: S24-S91

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

15.6 pg/ml - 1,000 pg/ml

Sensitivity :

<1 pg/ml

Sample Type :

cell culture supernatants, serum and plasma (heparin, EDTA, citrate)

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

C-C motif chemokine

Synonyms :

C-C motif chemokine ;Ccl5 ;rCG_35282 ;

Protein Name :

C-C motif chemokine 5

Molecular Weight :

10172 MW

Subcellular Localization :

Secreted .

Background :

Rantes (regulated on activation normal T cell expressed and secreted) is one of the natural ligands for the chemokine receptor CCR5 and potently suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Peripheral blood mononuclear cells or CD4 (+) lymphocytes obtained from different individuals have wide variations in their ability to secrete RANTES. The Rantes gene product is predicted to be 10 kDa and, after cleavage of the signal peptide, approximately 8 kDa. Of the 68 residues, 4 are cysteines, and there are no sites for N-linked glycosylation. Rantes is expressed by cultured T cell lines that are Ag specific and growth factor dependent.

Research Category :

Vascular Inflammation