Human OPN PicoKine ELISA Kit | Boster EK0482 product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human OPN PicoKine ELISA Kit

catalog :

EK0482

quantity :

96 wells/kit

price :

350 USD

more info or order :

Boster product webpage

product information

sku :

EK0482

name :

Human OPN PicoKine ELISA Kit

price :

350 USD

immunogen :

Expression system for standard: NSO; Immunogen sequence: I17-N300

description :

Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human OPN

size :

96 wells/kit

reactivity :

Human

applications :

ELISA

background :

Osteopontin(OPN) also called urinary stone protein, secreted phosphoprotein 1(SPP1), bone sialoprotein, and early T lymphocyte activation 1(ETA1). Osteopontin is a phosphorylated glycoprotein secreted to the mineralizing extrOPNllular matrix by osteoblasts during bone development. It is believed to facilitate the attachment of osteoblasts and osteoclasts to the extrOPNllular matrix, allowing them to perform their respective functions during osteogenesis. Osteopontin is presumably involved in stone formation as stone matrix. The deduced protein sequence reveals a 317-amino acid protein(34,982 Da) containing a 16-amino acid hydrophobic signal sequence and a 33,352-Da protein destines to undergo extensive post-translational modifications before being secreted from the cell. The gene is located on human chromosome 4. The standard product used in this kit is recombinant human OPN, consisting of 17-314 amino acid sequence with the molecular mass of 32.9KDa. As a result of glycosylation, the molecular mass is 60-65KDa.

cross reactivity :

There is no detectable cross-reactivity with other relevant proteins.

gene full name :

Osteopontin

gene name :

SPP1

protein function :

Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction.

protein name :

Osteopontin

research category :

cardiovascular angiogenesis adhesion / ecm extracellular matrix signal transduction cytoskeleton / ecm structures bone stem cells mesenchymal stem cells osteogenesis cancer tumor biomarkers

sequence similarities :

Belongs to the osteopontin family.

storage :

Store at 4ËšC for 6 months, at -20ËšC for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

subcellular localization :

Secreted.

synonyms :

Osteopontin;Bone sialoprotein 1;Nephropontin;Secreted phosphoprotein 1;SPP-1;Urinary stone protein;Uropontin;SPP1;BNSP, OPN;PSEC0156;

tissue specificity :

Bone. Found in plasma.

uniprot id :

P10451

more info or order :

Boster product webpage