Human NGF/NGF Beta PicoKine ELISA Kit | Boster EK0469 product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human NGF/NGF Beta PicoKine ELISA Kit

catalog :

EK0469

quantity :

96 wells/kit

price :

260 USD

more info or order :

Boster product webpage

product information

sku :

EK0469

name :

Human NGF/NGF Beta PicoKine ELISA Kit

price :

260 USD

immunogen :

Expression system for standard: NSO; Immunogen sequence: S122-A241

description :

Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human NGF/NGF beta

size :

96 wells/kit

reactivity :

Human

applications :

ELISA

background :

Nerve growth factor(NGF) is a polypeptide involved in the regulation of growth and differentiation of sympathetic and certain sensory neurons. NGF is thought to have a profound effect on the development and maintenance of sympathetic and embryonic sensory neurones. NGF activity isolated from the male mouse submaxillary gland(MSG) consists of three types of subunits, alpha, beta and gamma, which specifically interact to form a 7S, approximately 130,000-molecular weight(Mr) complex. The 7S complex contains two identical 118-amino acid beta-chains, which are solely responsible for the nerve growth-stimulating activity of NGF. NGF, which is expressed by inflammatory cells and effects changes that lead to increased neural responsiveness, could be a pivotal mediator in allergic rhinitis. The standard product used in this kit is human 2.5S NGF, which is a dimmer linking with two polypeptide chains of 120 amino acids.

cross reactivity :

There is no detectable cross-reactivity with other relevant proteins.

gene full name :

Beta-nerve growth factor

gene name :

NGF

protein function :

Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI (PubMed:20164177).

protein name :

Beta-nerve growth factor

research category :

neuroscience neurology process growth and development neurotrophins stem cells neural stem cells surface molecules mesenchymal stem cells

sequence similarities :

Belongs to the NGF-beta family.

storage :

Store at 4ËšC for 6 months, at -20ËšC for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

subcellular localization :

Secreted.

synonyms :

Beta-nerve growth factor;Beta-NGF;NGF;NGFB;

uniprot id :

P01138

more info or order :

Boster product webpage