Monkey primate NGF/NGF Beta ELISA Kit PicoKine® | Boster EK0469-PR product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Monkey primate NGF/NGF Beta ELISA Kit PicoKine®

catalog :

EK0469-PR

quantity :

96 wells/kit, with removable strips.

price :

369 USD

more info or order :

Boster product webpage

citations: 1

Reference
Li Y, Yang C, Lei L, Wu K, Yang P, Xiao W. Serum nerve grow factor and brain-derived neurotrophic factor profiles in Sjögren's syndrome concomitant with interstitial lung disease. Clin Rheumatol. 2014;33:1161-4 pubmed publisher

product information

SKU :

EK0469-PR

Product Name :

Monkey primate NGF/NGF Beta ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Price :

369 USD

Description :

Monkey primate NGF/NGF Beta ELISA Kit PicoKine® (96 Tests). Quantitate Monkey NGF in cell culture supernatants and serum. Sensitivity: 1pg/ml.

Reactivity :

Monkey

Application :

ELISA

Gene Name :

NGF

Uniprot ID :

P01138

Immunogen :

Expression system for standard: NS0; Immunogen sequence: S122-A241

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

15.6 pg/ml - 1,000 pg/ml

Sensitivity :

<1 pg/ml

Sample Type :

cell culture supernatants and serum

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Beta-nerve growth factor

Synonyms :

Beta-nerve growth factor;Beta-NGF;NGF;NGFB;

Protein Name :

Beta-nerve growth factor

Molecular Weight :

26959 MW

Protein Function :

Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI (PubMed:20164177).

Subcellular Localization :

Secreted.

Sequence Similarities :

Belongs to the NGF-beta family.

Background :

Nerve growth factor (NGF) is a polypeptide involved in the regulation of growth and differentiation of sympathetic and certain sensory neurons. NGF is thought to have a profound effect on the development and maintenance of sympathetic and embryonic sensory neurones. NGF activity isolated from the male monkey primate submaxillary gland (MSG) consists of three types of subunits, alpha, beta and gamma, which specifically interact to form a 7S, approximately 130,000-molecular weight (Mr) complex. The 7S complex contains two identical 118-amino acid beta-chains, which are solely responsible for the nerve growth-stimulating activity of NGF. NGF, which is expressed by inflammatory cells and effects changes that lead to increased neural responsiveness, could be a pivotal mediator in allergic rhinitis. The standard product used in this kit is monkey primate 2.5S NGF, which is a dimmer linking with two polypeptide chains of 120 amino acids.

Research Category :

Growth And Development, Mesenchymal Stem Cells, Neural Stem Cells, Neurology Process, Neuroscience, Stem Cells, Surface Molecules

more info or order :

Boster product webpage