Human MMP-10/Stromelysin-2 ELISA Kit PicoKine® | Boster EK0467 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human MMP-10/Stromelysin-2 ELISA Kit PicoKine®

catalog :

EK0467

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK0467

Product Name :

Human MMP-10/Stromelysin-2 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human MMP10 ELISA Kit PicoKine® (96 Tests). Quantitate Human MMP10 in cell culture supernatants, serum and plasma (heparin). Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

MMP10

Uniprot ID :

P09238

Immunogen :

Expression system for standard: NS0; Immunogen sequence: Y18-C476

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

78 pg/ml - 5,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, serum and plasma (heparin)

Capture/Detection Antibodies :

a monoclonal antibody from mouse, a biotinylated polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

matrix metallopeptidase 10

Synonyms :

Stromelysin-2; SL-2; 3.4.24.22; Matrix metalloproteinase-10; MMP-10; Transin-2; MMP10; STMY2;

Protein Function :

Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase.

Subcellular Localization :

Secreted, extracellular space, extracellular matrix .

Background :

Stromelysin-2 also known as matrix metalloproteinase-10 (MMP-10) or transin-2 is an enzyme that in humans is encoded by the MMP10 gene. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Research Category :

Angiogenesis, Cancer, Cardiovascular, Cell Biology, Ecm Enzymes, Extracellular Matrix, Invasion/Microenvironment, Metalloprotease, Proteolysis / Ubiquitin, Proteolytic Enzymes