Human CD25/IL-2sR Alpha ELISA Kit PicoKine® | Boster EK0400 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human CD25/IL-2sR Alpha ELISA Kit PicoKine®

catalog :

EK0400

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK0400

Product Name :

Human CD25/IL-2sR Alpha ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human CD25/IL-2sR Alpha ELISA Kit PicoKine® (96 Tests). Quantitate Human IL2RA in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 5pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

IL2RA

Uniprot ID :

P01589

Immunogen :

Expression system for standard: NS0; Immunogen sequence: E22-C213

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

78 pg/ml - 5,000 pg/ml

Sensitivity :

<5 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Interleukin-2 receptor subunit alpha

Synonyms :

Interleukin-2 receptor subunit alpha;IL-2 receptor subunit alpha;IL-2-RA;IL-2R subunit alpha;IL2-RA;TAC antigen;p55;CD25;IL2RA;

Protein Name :

Interleukin-2 receptor subunit alpha

Molecular Weight :

30819 MW

Protein Function :

Receptor for interleukin-2.

Subcellular Localization :

Membrane; Single-pass type I membrane protein.

Sequence Similarities :

Contains 2 Sushi (CCP/SCR) domains.

Background :

CD25 is the alpha chain of the IL-2 receptor. It is a type I transmembrane protein present on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes that associates with CD122 to form a heterodimer that can act as a high-affinity receptor for IL-2. The IL2R gene was mapped to 10p15-p14. CD25 is expressed in most B-cell neoplasms, some acute nonlymphocytic leukemias, neuroblastomas, and tumor infiltrating lymphocytes. Its soluble form, called sIL-2R may be elevated in these diseases and is occasionally used to track disease progression.

Research Category :

Adaptive Immunity, Cytokines, Immunology, Innate Immunity, Interleukins, T Cells