Mouse IGFBP-1 ELISA Kit PicoKine® | Boster EK0383 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse IGFBP-1 ELISA Kit PicoKine®

catalog :

EK0383

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK0383

Product Name :

Mouse IGFBP-1 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Mouse IGFBP-1 ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Igfbp1 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 3pg/ml.

Reactivity :

Mouse

Application :

ELISA

Gene Name :

IGFBP1

Uniprot ID :

P47876

Immunogen :

Expression system for standard: NS0; Immunogen sequence: A26-N272

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

31.2 pg/ml - 2,000 pg/ml

Sensitivity :

<3 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

polyclonal antibody from goat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Insulin-like growth factor-binding protein 1

Synonyms :

Insulin-like growth factor-binding protein 1;IBP-1;IGF-binding protein 1;IGFBP-1;Igfbp1;Igfbp-1;

Protein Name :

Insulin-like growth factor-binding protein 1

Molecular Weight :

29570 MW

Protein Function :

IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration (By similarity).

Subcellular Localization :

Secreted.

Sequence Similarities :

Contains 1 IGFBP N-terminal domain.

Background :

IGFBP1 is also known as amniotic fluid binding protein (AFBP), placental protein-12, alpha-pregnancy-associated endometrial globulin, growth hormone independent binding protein, binding protein-28, binding protein-26, and binding protein-25. The low-molecular weight insulin-like growth-factor binding protein (IGF-BP25) is synthesized by human liver, secretory endometrium and decidua, and is also present in human serum. It binds insulin-like growth factors IGF-I and IGF-II with high affinity, and is proposed to act as a paracrine regulator of cell growth. These IGF-binding proteins are expressed at different concentrations in different tissues and are thought to regulate the activity of IGF I and II. The gene is organized in four exons and spans 5.9 kb. The IBP-1 gene is a single copy gene, located on chromosome 7. The standard product used in this kit is recombinant mouse IGFBP-1, consisting of 247 amino acids with the molecular mass of 27KDa.

Research Category :

Signal Transduction