Mouse IGF-2 ELISA Kit PicoKine® | Boster EK0381 product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse IGF-2 ELISA Kit PicoKine®

catalog :

EK0381

quantity :

96 wells/kit, with removable strips.

price :

400 USD

more info or order :

Boster product webpage

citations: 1

Reference
Regué L, Ji F, Flicker D, Kramer D, Pierce W, Davidoff T, et al. IMP2 Increases Mouse Skeletal Muscle Mass and Voluntary Activity by Enhancing Autocrine Insulin-Like Growth Factor 2 Production and Optimizing Muscle Metabolism. Mol Cell Biol. 2019;39: pubmed publisher

image

image 1 :

Mouse IGF-2 PicoKine ELISA Kit standard curve

product information

SKU :

EK0381

Product Name :

Mouse IGF-2 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Price :

400 USD

Description :

Mouse IGF-2 ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Igf2 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 5pg/ml.

Reactivity :

Mouse

Application :

ELISA

Gene Name :

IGF2

Uniprot ID :

P09535

Immunogen :

Expression system for standard: E.coli; Immunogen sequence: A25-E91

Cross-reactivity :

There is no detectable cross-reactivity with IGF-1.

Assay Range :

62.5 pg/ml - 4,000 pg/ml

Sensitivity :

<5 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from rat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Insulin-like growth factor II

Synonyms :

Insulin-like growth factor II;IGF-II;Multiplication-stimulating polypeptide;Insulin-like growth factor II;Preptin;Igf2;Igf-2;

Protein Name :

Insulin-like growth factor II

Molecular Weight :

20030 MW

Protein Function :

The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development.

Subcellular Localization :

Secreted.

Background :

Insulin-like growth factor II is also known as somatomedin A. IGF-2 is a member of the insulin family of polypeptide growth factors that is involved in development and growth. It is paternally expressed in the fetus and placenta. IGF-II is a mitogen for many cell types and an important modulator of muscle growth and differentiation. IGF-II gene is prevalently expressed during prenatal development and its gene activity is regulated by genomic imprinting, in that the allele inherited from the father is active and the allele inherited from the mother is inactive in most normal tissues. IGF-II appears to be induced by placental lactogen during prenatal development. It is a mediator of prolactin-induced alveologenesis; prolactin, IGF-2, and cyclin D1, all of which are overexpressed in breast cancers, are components of a developmental pathway in the mammary gland.

Research Category :

Signal Transduction

more info or order :

Boster product webpage