Rat ICAM-1 ELISA Kit PicoKine® | Boster EK0372 product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Rat ICAM-1 ELISA Kit PicoKine®

catalog :

EK0372

quantity :

96 wells/kit, with removable strips.

price :

400 USD

more info or order :

Boster product webpage

citations: 1

Reference
Yang J, Zhao B, Han L, Liu P, Wang L, Bai H, et al. [Effects of controllable dynamic inhaled exposure of moxa smoke on LDL-r, ICAM-1 and morphology of heart tissue in rats]. Zhongguo Zhen Jiu. 2014;34:573-7 pubmed

image

image 1 :

Rat ICAM-1 PicoKine ELISA Kit standard curve

product information

SKU :

EK0372

Product Name :

Rat ICAM-1 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Price :

400 USD

Description :

Rat ICAM-1 ELISA Kit PicoKine® (96 Tests). Quantitate Rat ICAM1 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 2pg/ml.

Reactivity :

Rat

Application :

ELISA

Gene Name :

ICAM1

Uniprot ID :

P05362

Immunogen :

Expression system for standard: NS0; Immunogen sequence: Q28-T493

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

31.2 pg/ml - 2,000 pg/ml

Sensitivity :

<2 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Intercellular adhesion molecule 1

Synonyms :

Intercellular adhesion molecule 1;ICAM-1;Major group rhinovirus receptor;CD54;ICAM1;

Protein Name :

Intercellular adhesion molecule 1

Molecular Weight :

57825 MW

Protein Function :

ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans- endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.

Subcellular Localization :

Membrane; Single-pass type I membrane protein.

Sequence Similarities :

Belongs to the immunoglobulin superfamily. ICAM family.

Background :

Intercellular adhesion molecule-1 (ICAM-1) is an integral membrane protein, a member of the immunoglobulin superfamily, and a ligand for lymphocyte function-associated (LFA) antigens, a beta 2 leukocyte integrin. The normal function of human intercellular adhesion molecule-1 (ICAM-1) is to provide adhesion between endothelial cells and leukocytes after injury or stress. ICAM-1 binds to leukocyte function-associated antigen (LFA-1) or macrophage-1 antigen (Mac-1). ICAM-1 is found on leukocytes, fibroblasts, epithelial cells and endothelial cells and its expression is regulated by inflammatory cytokines. ICAM-1 has a tissue distribution similar to that of the major histocompatibility complex class II antigens and is likely to play a role in inflammatory responses. The standard product used in this kit is produced by recombinant gene expression, which is a dimeric protein linked with disulfide bonds.

Research Category :

Adaptive Immunity, Atherosclerosis, Cardiovascular, Cell Adhesion Molecules, Cell Type Markers, Hematopoietic Progenitors, Immunology, Lymphoid, Stem Cells, T Lymphocytic Lineage, Vascular Inflammation

more info or order :

Boster product webpage