Rat GDNF ELISA Kit PicoKine® | Boster EK0363 product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Rat GDNF ELISA Kit PicoKine®

catalog :

EK0363

quantity :

96 wells/kit, with removable strips.

price :

380 USD

more info or order :

Boster product webpage

citations: 1

Reference
Ikeda T, Xia X, Xia Y, Ikenoue T, Choi B. Expression of glial cell line-derived neurotrophic factor in the brain and cerebrospinal fluid of the developing rat. Int J Dev Neurosci. 1999;17:681-91 pubmed

image

image 1 :

Rat GDNF PicoKine ELISA Kit standard curve

product information

SKU :

EK0363

Product Name :

Rat GDNF ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Price :

380 USD

Description :

Rat GDNF ELISA Kit PicoKine® (96 Tests). Quantitate Rat GDNF in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 4pg/ml.

Reactivity :

Rat

Application :

ELISA

Gene Name :

GDNF

Uniprot ID :

A7UGJ1

Immunogen :

Expression system for standard: NS0; Immunogen sequence: S78-I211

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

31.2 pg/ml - 2,000 pg/ml

Sensitivity :

<4 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Glial cell line-derived neurotrophic factor

Synonyms :

Glial cell line-derived neurotrophic factor ;Gdnf ;

Protein Name :

Glial cell line-derived neurotrophic factor

Molecular Weight :

23619 MW

Protein Function :

Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.

Subcellular Localization :

Secreted .

Background :

Glial cell line-derived neurotrophic factor (GDNF) is a glycosylated, disulfide-bonded homodimer that is a distantly related member of the transforming growth factor-beta superfamily. GDNF, is a potent neurotrophic factor that promotes the survival of dopaminergic neurones in cultures including embryonic neuronal cultures. GDNF, in addition to its potential role in the differentiation and survival of central nervous system neurons, has profound effects on kidney organogenesis and the development of the peripheral nervous system.3 GDNF may have utility in the treatment of Parkinson's disease, which is marked by progressive degeneration of midbrain dopaminergic neurons. GDNF lies on the short arm of human chromosome 5, at 5p13.1-p13.3 ability to promote dopamine uptake in midbrain cultures. The standard product used in this kit is recombinant rat GDNF, which is a dimmer composed of two chains with 134 amino acids.

Research Category :

Developmental Biology, Growth And Development, Neurodegenerative Disease, Neurology Process, Neuroscience, Organogenesis

more info or order :

Boster product webpage