Mouse Flt-3ligand ELISA Kit PicoKine® | Boster EK0355 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse Flt-3ligand ELISA Kit PicoKine®

catalog :

EK0355

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK0355

Product Name :

Mouse Flt-3ligand ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Mouse Flt-3ligand ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Flt3lg in cell culture supernatants and serum. Sensitivity: 10pg/ml.

Reactivity :

Mouse

Application :

ELISA

Gene Name :

FLT3LG

Uniprot ID :

P49772

Immunogen :

Expression system for standard: NS0; Immunogen sequence: G27-R188

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

31.2 pg/ml - 2,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants and serum

Capture/Detection Antibodies :

monoclonal antibody from rat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Fms-related tyrosine kinase 3 ligand

Synonyms :

Fms-related tyrosine kinase 3 ligand;Flt3 ligand;Flt3L;SL cytokine;Flt3lg;Flt3l;

Protein Name :

Fms-related tyrosine kinase 3 ligand

Molecular Weight :

26141 MW

Protein Function :

Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins.

Subcellular Localization :

Cell membrane; Single-pass type I membrane protein.

Background :

Fms-related tyrosine kinase 3 ligand (FLT3LG), also known as Flt-3ligand or FL, is a protein which in humans is encoded by the FLT3LG gene. It is mapped to 19q13.3. Flt-3ligand is a hematopoietic four helical bundle cytokine. It is structurally homologous to stem cell factor (SCF) and colony stimulating factor 1 (CSF-1). In synergy with other growth factors, Flt-3ligand stimulates the proliferation and differentiation of various blood cell progenitors. Besides that, Flt-3ligand can control the development of Dendritic cells (DCs) and is particularly important for plasmacytoid DCs and CD8-positive classical DCs and their CD103-positive tissue counterparts. Flt-3ligand also can enhance the response of stem and primitive progenitor cells to other growth factors to generate all myeloid lineages except erythroid cells.

Research Category :

Angiogenesis, Cardiovascular, Cytokines, Immunology, Innate Immunity