Human Flt3 Ligand ELISA Kit PicoKine® | Boster EK0354 product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human Flt3 Ligand ELISA Kit PicoKine®

catalog :

EK0354

quantity :

96 wells/kit, with removable strips.

price :

369 USD

more info or order :

Boster product webpage

citations: 2

Reference
Fu J, Liu Y, Zhang X. [CD40 ligandization promotes IL-6 and Flt3 ligand production of bone marrow stromal cells]. Zhonghua Xue Ye Xue Za Zhi. 2002;23:585-7 pubmed
Gazitt Y, Liu Q. High steady-state plasma levels of flt3-ligand in the peripheral blood is a good predictor for poor mobilization of CD34+ PBSC in patients undergoing high-dose chemotherapy and stem cell rescue. J Hematother Stem Cell Res. 2000;9:285-93 pubmed

image

image 1 :

Human Flt-3ligand PicoKine ELISA Kit standard curve

product information

SKU :

EK0354

Product Name :

Human Flt3 Ligand ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Price :

369 USD

Description :

Human Flt3 Ligand ELISA Kit PicoKine® (96 Tests). Quantitate Human FLT3LG in cell culture supernatants, serum and plasma (heparin, EDTA, citrate). Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

FLT3LG

Uniprot ID :

P49771

Immunogen :

Expression system for standard: NS0; Immunogen sequence: T27-P185

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

15.6 pg/ml - 1,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, serum and plasma (heparin, EDTA, citrate)

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Fms-related tyrosine kinase 3 ligand

Synonyms :

Fms-related tyrosine kinase 3 ligand;Flt3 ligand;Flt3L;SL cytokine;FLT3LG;

Protein Name :

Fms-related tyrosine kinase 3 ligand

Molecular Weight :

26416 MW

Protein Function :

Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins.

Subcellular Localization :

Isoform 1: Cell membrane; Single-pass type I membrane protein.

Background :

Fms-related tyrosine kinase 3 ligand (FLT3LG), also known as Flt-3ligand or FL, is a protein which in humans is encoded by the FLT3LG gene. It is mapped to 19q13.3. Flt-3ligand is a hematopoietic four helical bundle cytokine. It is structurally homologous to stem cell factor (SCF) and colony stimulating factor 1 (CSF-1). In synergy with other growth factors, Flt-3ligand stimulates the proliferation and differentiation of various blood cell progenitors. Besides that, Flt-3ligand can control the development of Dendritic cells (DCs) and is particularly important for plasmacytoid DCs and CD8-positive classical DCs and their CD103-positive tissue counterparts. Flt-3ligand also can enhance the response of stem and primitive progenitor cells to other growth factors to generate all myeloid lineages except erythroid cells.

Research Category :

Angiogenesis, Cardiovascular, Cytokines, Immunology, Innate Immunity

more info or order :

Boster product webpage