Mouse FAS/Cd95 ELISA Kit PicoKine® | Boster EK0336 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse FAS/Cd95 ELISA Kit PicoKine®

catalog :

EK0336

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK0336

Product Name :

Mouse FAS/Cd95 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Mouse FAS/Cd95 ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Fas in cell culture supernatants, serum and plasma (heparin, EDTA, citrate). Sensitivity: 3pg/ml.

Reactivity :

Mouse

Application :

ELISA

Gene Name :

FAS

Uniprot ID :

Q8C350

Immunogen :

Expression system for standard: NS0; Immunogen sequence: Q22-R169

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

31.2 pg/ml - 2,000 pg/ml

Sensitivity :

<3 pg/ml

Sample Type :

cell culture supernatants, serum and plasma (heparin, EDTA, citrate)

Capture/Detection Antibodies :

monoclonal antibody from rat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Fas cell surface death receptor

Synonyms :

Tumor necrosis factor receptor superfamily member 6 ;Fas ;

Protein Name :

Tumor necrosis factor receptor superfamily member 6

Molecular Weight :

7116 MW

Background :

Fas, also known as APO-1, CD95 and TNFRSF6, is a member of the nerve growth factor (NGF)/tumour necrosis factor (TNF) receptor superfamily and mediates apoptosis. The nucleotide sequence of the cDNAs reveales that the molecule coding for the Fas antigen determinant is a 319 amino acid polypeptide with a single transmembrane domain. The extracellular domain is rich in cysteine residue, and shows a similarity to that of human tumor necrosis factor receptors, human nerve growth factor receptor, and human B cell antigen CD40. The APO-1 antigen as defined by the mouse monoclonal antibody anti-APO-1 is previously found to be expressed on the cell surface of activated human T and B lymphocytes and a variety of malignant human lymphoid cell lines. The APO-1 antigen is found to be a membrane glycoprotein of 48-kDa. Fas antigen is expressed and functional on papillary thyroid cancer cells and this may have potential therapeutic significance. Fas can play a role as an inducer of both neurite growth in vitro and accelerates recovery after nerve injury in vivo.

Research Category :

Adaptive Immunity, Apoptosis, Autoimmune, Cell Biology, Cytokines, Hematopoietic Progenitors, Immune System Diseases, Immunology, Innate Immunity, Lymphoid, Stem Cells, T Lymphocytic Lineage, Tnf Superfamily