Human CCL24/Eotaxin-2 ELISA Kit PicoKine® | Boster EK0331 product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human CCL24/Eotaxin-2 ELISA Kit PicoKine®

catalog :

EK0331

quantity :

96 wells/kit, with removable strips.

price :

369 USD

more info or order :

Boster product webpage

citations: 1

Reference
Sharifabadi A, Hassanshahi G, Ghalebi S, Arababadi M, Khorramdelazad H, Zainodini N, et al. All eotaxins CCL11, CCL24 and CCL26 are increased but to various extents in pulmonary tuberculosis patients. Clin Lab. 2014;60:93-7 pubmed

image

image 1 :

Human CCL24/Eotaxin-2 PicoKine ELISA Kit standard curve

product information

SKU :

EK0331

Product Name :

Human CCL24/Eotaxin-2 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Price :

369 USD

Description :

Human CCL24/Eotaxin-2 ELISA Kit PicoKine® (96 Tests). Quantitate Human CCL24 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 2 pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

CCL24

Uniprot ID :

O00175

Immunogen :

Expression system for standard: E.coli; Immunogen sequence: V27-C119

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

31.2 pg/ml - 2,000 pg/ml

Sensitivity :

<2 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

polyclonal antibody from goat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

C-C motif chemokine 24

Synonyms :

C-C motif chemokine 24;CK-beta-6;Eosinophil chemotactic protein 2;Eotaxin-2;Myeloid progenitor inhibitory factor 2;MPIF-2;Small-inducible cytokine A24;CCL24;MPIF2, SCYA24;

Protein Name :

C-C motif chemokine 24

Molecular Weight :

13134 MW

Protein Function :

Chemotactic for resting T-lymphocytes, and eosinophils. Has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. Is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. Binds to CCR3.

Subcellular Localization :

Secreted.

Tissue Specificity :

Activated monocytes and activated T lymphocytes.

Sequence Similarities :

Belongs to the intercrine beta (chemokine CC) family.

Background :

Chemokine (C-C motif) ligand 24 (CCL24) also known as myeloid progenitor inhibitory factor 2 (MPIF-2) or eosinophil chemotactic protein 2 (eotaxin-2) is a protein that in humans is encoded by the CCL24 gene. By use of PCR analysis of somatic cell hybrid DNAs, radiation hybrid mapping, and a chromosome 7-specific YAC library, mapped the SCYA24 gene to chromosome 7q11.23. CCL24 is a small cytokine belonging to the CC chemokine family. CCL24 interacts with chemokine receptor CCR3 to induce chemotaxis in eosinophils.3 This chemokine is also strongly chemotactic for resting T lymphocytes and slightly chemotactic for neutrophils.

Research Category :

Chemokines, Immunology, Innate Immunity

more info or order :

Boster product webpage