Mouse Eotaxin-1 ELISA Kit PicoKine® | Boster EK0330 product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse Eotaxin-1 ELISA Kit PicoKine®

catalog :

EK0330

quantity :

96 wells/kit, with removable strips.

price :

369 USD

more info or order :

Boster product webpage

citations: 1

Reference
Eum S, Maghni K, Hamid Q, Eidelman D, Campbell H, Isogai S, et al. Inhibition of allergic airways inflammation and airway hyperresponsiveness in mice by dexamethasone: role of eosinophils, IL-5, eotaxin, and IL-13. J Allergy Clin Immunol. 2003;111:1049-61 pubmed

image

image 1 :

Mouse Eotaxin PicoKine ELISA Kit standard curve

product information

SKU :

EK0330

Product Name :

Mouse Eotaxin-1 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Price :

369 USD

Description :

Mouse Eotaxin-1 ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Ccl11 in cell culture supernatants, serum and plasma (citrate, EDTA). Sensitivity: 1pg/ml.

Reactivity :

Mouse

Application :

ELISA

Gene Name :

CCL11

Uniprot ID :

P48298

Immunogen :

Expression system for standard: E.coli; Immunogen sequence: H24-P97

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

15.6 pg/ml - 1,000 pg/ml

Sensitivity :

<1 pg/ml

Sample Type :

cell culture supernatants, serum and plasma (citrate, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from rat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Eotaxin

Synonyms :

Eotaxin;C-C motif chemokine 11;Eosinophil chemotactic protein;Small-inducible cytokine A11;Ccl11;Scya11;

Protein Name :

Eotaxin

Molecular Weight :

10893 MW

Protein Function :

In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils (a prominent feature of allergic inflammatory reactions), but not lymphocytes, macrophages or neutrophils.

Subcellular Localization :

Secreted.

Tissue Specificity :

Expressed constitutively in the thymus. Expression inducible in the lung (type I alveolar epithelial cells), intestine, heart, spleen, kidney.

Background :

Eotaxin, also known as CCL11, is a potent inducer of eosinophil chemotaxis and is considered as a selective ligand of the CC chemokine receptor 3 (CCR3), which is expressed on eosinophils, basophils, and Th2 lymphocytes. Eotaxin is assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. The gene maps to chromosome 17 and is expressed constitutively at high levels in small intestine and colon, and at lower levels in various other tissues. The deduced mature protein sequence is 66% identical to human monocyte chemoattractant protein-1, and 60% identical to guinea pig eotaxin.

Research Category :

Chemokines, Immunology, Innate Immunity

more info or order :

Boster product webpage