Mouse EGF ELISA Kit PicoKine® | Boster EK0326 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse EGF ELISA Kit PicoKine®

catalog :

EK0326

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK0326

Product Name :

Mouse EGF ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Mouse EGF ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Egf in cell culture supernatants, serum, plasma (heparin, EDTA) and urine. Sensitivity: 1pg/ml.

Reactivity :

Mouse

Application :

ELISA

Gene Name :

EGF

Uniprot ID :

P01132

Immunogen :

Expression system for standard: E.coli; Immunogen sequence: N977-R1029

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

7.8 pg/ml - 500 pg/ml

Sensitivity :

<1 pg/ml

Sample Type :

cell culture supernatants, serum, plasma (heparin, EDTA) and urine

Capture/Detection Antibodies :

monoclonal antibody from rat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Pro-epidermal growth factor

Synonyms :

Pro-epidermal growth factor;EGF;Epidermal growth factor;Egf;

Protein Name :

Pro-epidermal growth factor

Molecular Weight :

133072 MW

Protein Function :

EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).

Subcellular Localization :

Membrane; Single-pass type I membrane protein.

Sequence Similarities :

Contains 9 EGF-like domains.

Background :

Epidermal growth factor or EGF is a growth factor that plays an important role in the regulation of cell growth, proliferation, and differentiation by binding to its receptor EGFR. EGF acts by binding with high affinity to epidermal growth factor receptor (EGFR) on the cell surface and stimulating the intrinsic protein-tyrosine kinase activity of the receptor. EGF results in cellular proliferation, differentiation, and survival. It also has a profound effect on the differentiation of specific cells in vivo and is a potent mitogenic factor for a variety of cultured cells of both ectodermal and mesodermal origin. EGF has strong expression in kidney, salivary gland, cerebrum, and prostate, moderate expression in trachea and thyroid, and low expression in bone marrow, heart, spleen, thymus, uterus, and colon. No expression was detected in adrenal gland, liver, lung, cerebellum, placenta, and small intestine.

Research Category :

Cancer, Cell Biology, Cell Cycle, Cell Differentiation, Growth Factors, Growth Factors/Hormones, Signal Transduction