Rat CNTF ELISA Kit PicoKine® | Boster EK0324 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Rat CNTF ELISA Kit PicoKine®

catalog :

EK0324

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK0324

Product Name :

Rat CNTF ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Rat CNTF ELISA Kit PicoKine® (96 Tests). Quantitate Rat Cntf in cell culture supernatants, serum and plasma (heparin, EDTA, citrate). Sensitivity: 10pg/ml.

Reactivity :

Rat

Application :

ELISA

Gene Name :

CNTF

Uniprot ID :

P20294

Immunogen :

Expression system for standard: E.coli; Immunogen sequence: A2-M200

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

31.2 pg/ml - 2,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, serum and plasma (heparin, EDTA, citrate)

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Ciliary neurotrophic factor

Synonyms :

Ciliary neurotrophic factor;CNTF;Cntf;

Protein Name :

Ciliary neurotrophic factor

Molecular Weight :

22854 MW

Protein Function :

CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.

Subcellular Localization :

Cytoplasm

Tissue Specificity :

Nervous system

Background :

Ciliary neurotrophic factor (CNTF) is a potent polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes survival, neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The hCNTF gene is located on chromosome 11, as determined using human-hamster somatic cell hybrids. The CNTF protein is highly conserved in evolution. The amino acid (aa) sequences of rat and rabbit CNTF translated from cDNAs display approx. 85% homology with the deduced aa sequence encoding hCNTF. CNTF induces weight loss and improves glucose tolerance in humans and rodents. CNTF is thought to act centrally by inducing hypothalamic neurogenesis to modulate food intake and peripherally by altering hepatic gene expression, in a manner similar to that of leptin.

Research Category :

Cell Type Marker, Growth And Development, Neural Stem Cells, Neurology Process, Neuroscience, Stem Cells