Rabbit BMP-2 ELISA Kit PicoKine® | Boster EK0311-RB product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Rabbit BMP-2 ELISA Kit PicoKine®

catalog :

EK0311-RB

quantity :

96 wells/kit, with removable strips.

price :

400 USD

more info or order :

Boster product webpage

citations: 1

Reference
ToÅ¡ovskÃ½ M, Bradna P, AndrÃ½s C, AndrÃ½sovÃ¡ K, CermÃ¡kovÃ¡ E, Soukup T. The VEGF and BMP-2 levels in patients with ankylosing spondylitis and the relationship to treatment with tumour necrosis factor alpha inhibitors. Acta Medica (Hradec Kralove). 2014;57:56-61 pubmed publisher

product information

SKU :

EK0311-RB

Product Name :

Rabbit BMP-2 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Price :

400 USD

Description :

Rabbit BMP-2 ELISA Kit PicoKine® (96 Tests). Quantitate Rabbit BMP2 in bone tissue, cell culture supernatants and serum. Sensitivity: 2pg/ml.

Reactivity :

Rabbit

Application :

ELISA

Gene Name :

BMP2

Uniprot ID :

C8C060

Immunogen :

Expression system for standard: CHO; Immunogen sequence: Q283-R396

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

31.2 pg/ml - 2,000 pg/ml

Sensitivity :

<2 pg/ml

Sample Type :

bone tissue, cell culture supernatants and serum

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

bone morphogenetic protein 2

Synonyms :

Bone morphogenetic protein 2 ;BMP2 ;

Protein Name :

Bone morphogenetic protein 2

Molecular Weight :

44702 MW

Background :

Bone morphogenetic protein-2 (BMP-2, BMP 2A) belongs to the transforming growth factor beta (TGF-beta) superfamily. It is thought to be involved in cartilage and bone formation during embryogenesis, but may have additional functions in morphogenesis as implied by its expression in various organs and embryonic tissues of mice.1 BMP-2 has been identified as a candidate mediator of retinoid activity. BMP-2 protein induces medulloblastoma cell apoptosis, whereas the BMP-2 antagonist noggin blocks both retinoid and BMP-2-induced apoptosis. BMP-2 also induces p38 mitogen-activated protein kinase (MAPK), which is necessary for BMP-2 and retinoid-induced apoptosis.2 Bone morphogenic proteins (BMPs) are known to promote osteogenesis, and clinical trials are currently underway to evaluate the ability of certain BMPs to promote fracture-healing and spinal fusion.3 The standard product used in this kit is recombinant rabbit BMP-2, constituting dimer by two chains of 114 amino acids with the molecular mass of 26KDa.

Research Category :

Angiogenesis, Cancer, Cardiovascular, Cytoskeleton / Ecm, Extracellular Matrix, Growth Factors, Growth Factors/Hormones, Neural Stem Cells, Secreted, Signal Transduction, Signaling Pathways, Stem Cells, Structures, Tgf Beta

more info or order :

Boster product webpage