Mouse Activin A ELISA Kit PicoKine® | Boster EK0302 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse Activin A ELISA Kit PicoKine®

catalog :

EK0302

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK0302

Product Name :

Mouse Activin A ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Mouse Activin A ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Inhba in cell culture supernatants, serum, plasma (heparin, EDTA) and saliva. Sensitivity: 10pg/ml.

Reactivity :

Mouse

Predicted Reactivity :

Bovine, Monkey, Rabbit

Application :

ELISA

Gene Name :

INHBA

Uniprot ID :

Q04998

Immunogen :

Expression system for standard: CHO; Immunogen sequence: G311-S426

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

15.6 pg/ml - 1,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, serum, plasma (heparin, EDTA) and saliva

Capture/Detection Antibodies :

monoclonal antibody from mouse, monoclonal antibody from mouse

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Inhibin beta A chain

Synonyms :

Inhibin beta A chain;Activin beta-A chain;Inhba;

Protein Name :

Inhibin beta A chain

Molecular Weight :

47392 MW

Protein Function :

Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.

Subcellular Localization :

Secreted.

Tissue Specificity :

Uterus, ovary and liver.

Background :

Activin A is a homodimer of 14kDa beta-A. Activin A, a cytokine member of the transforming growth factor-beta superfamily, is expressed locally by the mesenchymal component of the hemopoietic microenvironment. Its expression is regulated on the mRNA level by different cytokines, and the biological activity of the protein is tightly controlled by several inhibitory molecules. Inhibins and activins are members of the transforming growth factor beta superfamily and are known to modulate the growth and differentiation of several cell types. Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. The standard product used in this kit is recombinant Activin A, which is composed of two single chains of 116 amino acids with the molecular mass of 26KDa.

Research Category :

Cancer, Growth Factors/Hormones, Signal Transduction, Tumor Biomarkers