Anti-BCMA TNFRSF17 Antibody (Monoclonal, Vicky-1), PE Conjugated

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-BCMA TNFRSF17 Antibody (Monoclonal, Vicky-1), PE Conjugated

catalog :

E01014

quantity :

100µg/vial

clonality :

monoclonal

host :

rat

conjugate :

clone name :

Vicky-1

The same clone is also sold as:

Novus Biologicals: NBP1-97637
Invitrogen: MA1-25953

reactivity :

human

application :

flow cytometry

product information

SKU :

E01014

Product Name :

Anti-BCMA TNFRSF17 Antibody (Monoclonal, Vicky-1), PE Conjugated

Size :

100µg/vial

Clonality :

Monoclonal

Clone Number :

Vicky-1

Host :

Rat

Conjugate :

Reactivity :

Human

Application(s) :

Flow Cytometry

Application Details :

Flow Cytometry, 1:100, Human

Description :

Boster Bio Anti-BCMA TNFRSF17 Antibody (Monoclonal, Vicky-1), PE Conjugated catalog # E01014. Tested in Flow Cytometry applications. This antibody reacts with Human.

Concentration :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

TNFRSF17

Uniprot ID :

Q02223

Immunogen :

Recombinant human BCMA extracellular domain (aa 2-54).

Form :

Liquid

Contents :

Each vial contains 0.02% sodium azide.

Purification :

Protein G-affinity purified.

Cross-reactivity :

No cross reactivity with other proteins.

Gene Full Name :

Tumor necrosis factor receptor superfamily member 17

Synonyms :

Tumor necrosis factor receptor superfamily member 17; B-cell maturation protein; CD269; TNFRSF17; BCM, BCMA;

Protein Name :

Tumor necrosis factor receptor superfamily member 17 (TNFRSF17)

Molecular Weight :

20165 MW

Protein Function :

Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.

Subcellular Localization :

Cell membrane; Single-pass type III membrane protein. Endomembrane system; Single-pass type III membrane protein. Perinuclear Golgi-like structures.

Tissue Specificity :

Expressed in mature B-cells, but not in T- cells or monocytes.

Background :

TNFRSF17 (Tumor necrosis factor receptor superfamily member 17), also called BCMA, is a protein that in humans is encoded by the TNFRSF17 gene. The protein encoded by this gene is a member of the TNF-receptor superfamily and is mapped to 16p13.13. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.

Research Category :

Antiviral Signaling, Cancer, Growth Factors, Growth Factors/Hormones, Immune System Diseases, Immunology, Signal Transduction