Anti-Zebrafish CHD7 Antibody | Boster DZ01533 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Zebrafish CHD7 Antibody

catalog :

DZ01533

quantity :

200μl/vial

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

zebrafish

product information

SKU :

DZ01533

Product Name :

Anti-Zebrafish CHD7 Antibody

Size :

200μl/vial

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

zebrafish

Application Notes :

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Polyclonal Anti-CHD7 Antibody catalog # DZ01533. This antibody reacts with Zebrafish.

Concentration :

500μg/ml

Gene Name :

chd7

Uniprot ID :

F1QGL1

Form :

Liquid

Contents :

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Purification :

Immunogen affinity purified.

Cross-reactivity :

No cross reactivity with other proteins.

Storage :

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Gene Full Name :

RAB11B,member RAS oncogene family

Synonyms :

Ras-related protein Rab-11B; GTP-binding protein YPT3; RAB11B; YPT3

Protein Name :

Ras-related protein Rab-11B

Protein Function :

The small GTPases Rab are key regulators of intracellular membrane trafficking,from the formation of transport vesicles to their fusion with membranes.Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation,movement,tethering and fusion.That Rab plays a role in endocytic recycling,regulating apical recycling of several transmembrane proteins including cystic fibrosis transmembrane conductance regulator/CFTR,epithelial sodium channel/ENaC,potassium voltage- gated channel,and voltage-dependent L-type calcium channel.May also regulate constitutive and regulated secretion,like insulin granule exocytosis.Required for melanosome transport and release from melanocytes.Also regulates V-ATPase intracellular transport in response to extracellular acidosis.

Subcellular Localization :

Recycling endosome membrane;Lipid-anchor;Cytoplasmic side.Cytoplasmic vesicle,secretory vesicle,synaptic vesicle membrane;Lipid-anchor;Cytoplasmic side.Cytoplasmic vesicle,phagosome membrane;Lipid-anchor;Cytoplasmic side.Recruited to phagosomes containing S.aureus.

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P) and ICC.

Background :

Ras-related protein Rab-11B is a protein that in humans is encoded by the RAB11B gene. It is mapped to 19p13.2. The Ras superfamily of small GTP-binding proteins, which includes the Ras, Ral, Rho, Rap, and Rab families, is involved in controlling a diverse set of essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating exocytotic and endocytotic pathways.