Anti-Fruit fly DLG Antibody | Boster DZ01287 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Fruit fly DLG Antibody

catalog :

DZ01287

quantity :

200μl/vial

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

fruit fly

product information

SKU :

DZ01287

Product Name :

Anti-Fruit fly DLG Antibody

Size :

200μl/vial

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Fruit fly

Application Notes :

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Polyclonal Anti-DLG Antibody catalog # DZ01287. This antibody reacts with Fruit fly.

Concentration :

500μg/ml

Gene Name :

dlg1

Uniprot ID :

P31007

Form :

Liquid

Contents :

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Purification :

Immunogen affinity purified.

Cross-reactivity :

No cross reactivity with other proteins.

Storage :

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Gene Full Name :

mitofusin 1

Synonyms :

Fzo homolog antibody Hfzo1 antibody Hfzo2 antibody MFN 1 antibody Mfn1 antibody MFN1_HUMAN antibody Mitochondrial transmembrane GTPase Fzo 1 antibody Mitochondrial transmembrane GTPase FZO 2 antibody Mitochondrial transmembrane GTPaseFZO1B antibody Mitofusin 1 antibody Mitofusin-1 antibody Mitofusin1 antibody Putative transmembrane GTPase antibody Transmembrane GTPase MFN1 antibody

Protein Name :

Mitofusin-1

Protein Function :

Essential transmembrane GTPase,which mediates mitochondrial fusion.Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology,which is balanced between fusion and fission.MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks.

Subcellular Localization :

Mitochondrion outer membrane ; Multi- pass membrane protein.

Tissue Specificity :

Ubiquitous.Expressed at slightly higher level in kidney and heart.Isoform 2 may be overexpressed in some tumors,such as lung cancers.

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti- Mouse IgG Super Vision Assay Kit (SV0001-1) for ICC.

Background :

Mitofusin-1 is a protein that in humans is encoded by the MFN1 gene. It is an 8090 kDa mitochondrial member of the dynamin family of molecules. It is ubiquitously expressed, and found in the outer mitochondrial membrane. The protein encoded by this gene is a mediator of mitochondrial fusion, and thereby contribute to the dynamic balance between fusion and fission that determines mitochondria morphology. MFN1 is known to form oligomers, either with itself or MFN2, and to undergo ubiquitination by MARCH5. MFN1 has two key domains. One is a coiledcoil region that mediates MFN1: MFN1/2 binding, and a second is a GTPase domain whose cleavage of GTP is necessary for membrane fusion. Overexpression of MFN1 caused perinuclear mitochondrial clustering.