Anti-Fruit fly Discs Large 1 Antibody | Boster DZ01287-1 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Fruit fly Discs Large 1 Antibody

catalog :

DZ01287-1

quantity :

200μl/vial

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

fruit fly

product information

SKU :

DZ01287-1

Product Name :

Anti-Fruit fly Discs Large 1 Antibody

Size :

200μl/vial

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Fruit fly

Application Notes :

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Polyclonal Anti-Discs Large 1 Antibody catalog # DZ01287-1. This antibody reacts with Fruit fly.

Concentration :

500μg/ml

Gene Name :

dlg1

Uniprot ID :

P31007

Form :

Liquid

Contents :

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Purification :

Immunogen affinity purified.

Cross-reactivity :

No cross reactivity with other proteins.

Storage :

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Gene Full Name :

high mobility group box 3

Synonyms :

chromosomal protein, Nonhistone, HMG4 antibody High mobility group (nonhistone chromosomal) protein 4 antibody High mobility group box 3 antibody High mobility group protein 2a antibody High mobility group protein 4 antibody High mobility group protein B3 antibody High mobility group protein HMG4 antibody HMG 4 antibody HMG-2a antibody HMG-4 antibody HMG2A antibody HMGB 3 antibody HMGB3 antibody HMGB3_HUMAN antibody MGC90319 antibody Non histone chromosomal protein antibody Nonhistone chromosomal protein HMG4 antibody

Protein Name :

High mobility group protein B3

Protein Function :

Multifunctional protein with various roles in different cellular compartments,May act in a redox sensitive manner.Associates with chromatin and binds DNA with a preference to non- canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters (By similarity).Proposed to be involved in the innate immune response to nucleic acids by acting as a cytoplasmic promiscuous immunogenic DNA/RNA sensor (By similarity).Negatively regulates B-cell and myeloid cell differentiation.In hematopoietic stem cells may regulate the balance between self-renewal and differentiation. Involved in negative regulation of canonical Wnt signaling (By similarity).

Subcellular Localization :

Nucleus. Chromosome. Cytoplasm.

Tissue Specificity :

Expressed predominantly in placenta.

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti- Mouse IgG Super Vision Assay Kit (SV0001-1) for ICC.

Background :

High-mobility group protein B, also known as HMG4, is a protein that in humans is encoded by the HMGB3 gene. This gene encodes a member of a family of proteins containing one or more high mobility group DNA-binding motifs. The encoded protein plays an important role in maintaining stem cell populations, and may be aberrantly expressed in tumor cells. A mutation in this gene was associated with microphthalmia, syndromic 13. There are numerous pseudogenes of this gene on multiple chromosomes. Alternative splicing results in multiple transcript variants.