Anti-H3K27me3 Antibody (Monoclonal) | Boster CI1146 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-H3K27me3 Antibody (Monoclonal)

catalog :

CI1146

quantity :

50 ug/50 ul

price :

380 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunocytochemistry, chromatin immunoprecipitation

product information

sku :

CI1146

name :

Anti-H3K27me3 Antibody (Monoclonal)

price :

380 USD

immunogen :

This antibody is raised in mouse against histone H3 trimethylated at lysine 27 (H3K27me3), using a KLH-conjugated synthetic peptide.

form :

Liquid

host :

Mouse

contents :

Protein A purified monoclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300.

purification :

Protein A purified

clonality :

Monoclonal

description :

Mouse monoclonal antibody for histone H3 trimethylated at lysine 27 (H3K27me3). Tested with ChIP,ELISA,WB,IF, in Human.

size :

50 ug/50 ul

reactivity :

Human

applications :

ChIP; ChIP-qPCR; ELISA; IF; WB

background :

Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome. Histone tails undergo numerous post-translational modifications, which either directly or indirectly alter chromatin structure to facilitate transcriptional activation or repression or other nuclear processes. In addition to the genetic code, combinations of the different histone modifications reveal the so-called â€œhistone codeâ€. Histone methylation and demethylation is dynamically regulated by respectively histone methyl transferases and histone demethylases.

gene full name :

Histone H3.1

gene name :

HIST1H3A

protein function :

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

protein name :

Histone H3.1

research category :

epigenetics and nuclear signaling histones h3 unmodified epigenetics and nuclear signaling chip'ing antibodies isotype/loading controls histone h3

storage :

At -20 for one year, at 4 for one month. Avoid repeated freezing and thawing.

subcellular localization :

Nucleus. Chromosome.

synonyms :

Histone H3.1;Histone H3/a;Histone H3/b;Histone H3/c;Histone H3/d;Histone H3/f;Histone H3/h;Histone H3/i;Histone H3/j;Histone H3/k;Histone H3/l;HIST1H3A;H3FA;HIST1H3B;H3FL;HIST1H3C;H3FC;HIST1H3D;H3FB;HIST1H3E;H3FD;HIST1H3F;H3FI;HIST1H3G;H3FH;HIST1H3H;H3FK;HIST1H3I;H3FF;HIST1H3J;H3FJ;

uniprot id :

P68431