Anti-H2AK5ac Antibody | Boster CI1078 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-H2AK5ac Antibody

catalog :

CI1078

quantity :

50 ug/ 54 ul

price :

380 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, chromatin immunoprecipitation, ChIP-Seq

product information

sku :

CI1078

name :

Anti-H2AK5ac Antibody

price :

380 USD

immunogen :

This antibody is raised in rabbit against the region of histone H2A containing the acetylated lysine 5 (H2AK5ac), using a KLH-conjugated synthetic peptide.

form :

Liquid

host :

Rabbit

contents :

Affinity purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300.

purification :

Affinity purified

clonality :

Polyclonal

description :

Rabbit IgG polyclonal antibody for the region of histone H2A containing the acetylated lysine 5 (H2AK5ac). Tested with ChIP,ELISA,Dot blot,WB in Human.

size :

50 ug/ 54 ul

reactivity :

Human

applications :

ChIP; ChIP-qPCR; ChIP-seq; Dot blot; ELISA; WB

background :

Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Two core histones of each class H2A, H2A, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome. Histone tails undergo numerous post-translational modifications, which either directly or indirectly alter chromatin structure to facilitate transcriptional activation or repression or other nuclear processes. In addition to the genetic code, combinations of the different histone modifications reveal the so-called â€œhistone codeâ€. Histone methylation and demethylation is dynamically regulated by respectively histone methyl transferases and histone demethylases.

gene full name :

Histone H2A type 1-B/E

gene name :

HIST1H2AB

protein function :

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

protein name :

Histone H2A type 1-B/E

research category :

epigenetics and nuclear signaling histones h2a crotonylated

storage :

At -20 for one year, at 4 for one month. Avoid repeated freezing and thawing.

subcellular localization :

Nucleus. Chromosome.

synonyms :

Histone H2A type 1-B/E;Histone H2A.2;Histone H2A/a;Histone H2A/m;HIST1H2AB;H2AFM;HIST1H2AE;H2AFA;

uniprot id :

P04908