This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Boster
product type :
antibody
product name :
Anti-H4pan Antibody
catalog :
CI1069
quantity :
50 ug/44 ul
price :
380 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
chromatin immunoprecipitation
product information
sku :
CI1069
name :
Anti-H4pan Antibody
price :
380 USD
immunogen :
This antibody is raised in rabbit against histone H4 using a KLH-conjugated synthetic peptide containing an unmodified sequence from the central part of the protein.
form :
Liquid
host :
Rabbit
contents :
Affinity purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300.
purification :
Affinity purified
clonality :
Polyclonal
description :
Rabbit IgG polyclonal antibody for histone H4. Tested with ChIP,ELISA,Dot blot in Human.
size :
50 ug/44 ul
reactivity :
Human
applications :
ChIP; ChIP-qPCR; Dot blot; ELISA
background :
Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome. Histones play a central role in the regulation of transcription, DNA repair, DNA replication and chromosomal stability. These different functions are established via a complex set of post-translational modifications which either directly or indirectly alter chromatin structure and DNA accessibility to facilitate transcriptional activation or repression or other nuclear processes.
gene full name :
Histone H4
gene name :
HIST1H4A
protein function :
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
protein name :
Histone H4
research category :
epigenetics and nuclear signaling histones h4 unmodified epigenetics and nuclear signaling chip'ing antibodies
sequence similarities :
Belongs to the histone H4 family.
storage :
At -20 for one year, at 4 for one month. Avoid repeated freezing and thawing.
subcellular localization :
Nucleus. Chromosome.
synonyms :
Histone H4;HIST1H4A;H4/A, H4FA;HIST1H4B;H4/I, H4FI;HIST1H4C;H4/G, H4FG;HIST1H4D;H4/B, H4FB;HIST1H4E;H4/J, H4FJ;HIST1H4F;H4/C, H4FC;HIST1H4H;H4/H, H4FH;HIST1H4I;H4/M, H4FM;HIST1H4J;H4/E, H4FE;HIST1H4K;H4/D, H4FD;HIST1H4L;H4/K, H4FK;HIST2H4A;H4/N, H4F2, H4FN, HIST2H4;HIST2H4B;H4/O, H4FO;HIST4H4;
uniprot id :
P62805
company information
Boster
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
https://www.bosterbio.com
925.485.4527
headquarters: USA
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