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product summary
company name :
Boster
product type :
antibody
product name :
Anti-H4K20me1 Antibody
catalog :
CI1005
quantity :
100 ul
price :
380 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, chromatin immunoprecipitation
product information
sku :
CI1005
name :
Anti-H4K20me1 Antibody
price :
380 USD
immunogen :
This antibody is raised in rabbit against histone H4 containing the monomethylated lysine 20 (H4K20me1), using a KLH-conjugated synthetic peptide.
form :
Liquid
host :
Rabbit
contents :
Whole antiserum from rabbit containing 0.05% azide.
purification :
Whole antiserum
clonality :
Polyclonal
description :
Rabbit IgG polyclonal antibody for histone H4 containing the monomethylated lysine 20 (H4K20me1). Tested with ChIP,ELISA,Dot blot,WB in Human.
size :
100 ul
reactivity :
Human
applications :
ChIP; ChIP-qPCR; Dot blot; ELISA; WB
background :
Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome. Histone tails undergo numerous post-translational modifications, which either directly or indirectly alter chromatin structure to facilitate transcriptional activation or repression or other nuclear processes. In addition to the genetic code, combinations of the different histone modifications reveal the so-called “histone code”. Histone methylation and demethylation is dynamically regulated by respectively histone methyl transferases and histone demethylases.
gene full name :
Histone H4
gene name :
HIST1H4A
protein function :
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
protein name :
Histone H4
research category :
epigenetics and nuclear signaling histones h4 unmodified epigenetics and nuclear signaling chip'ing antibodies
sequence similarities :
Belongs to the histone H4 family.
storage :
At -20 for one year, at 4 for one month. Avoid repeated freezing and thawing.
subcellular localization :
Nucleus. Chromosome.
synonyms :
Histone H4;HIST1H4A;H4/A, H4FA;HIST1H4B;H4/I, H4FI;HIST1H4C;H4/G, H4FG;HIST1H4D;H4/B, H4FB;HIST1H4E;H4/J, H4FJ;HIST1H4F;H4/C, H4FC;HIST1H4H;H4/H, H4FH;HIST1H4I;H4/M, H4FM;HIST1H4J;H4/E, H4FE;HIST1H4K;H4/D, H4FD;HIST1H4L;H4/K, H4FK;HIST2H4A;H4/N, H4F2, H4FN, HIST2H4;HIST2H4B;H4/O, H4FO;HIST4H4;
uniprot id :
P62805
company information
Boster
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
https://www.bosterbio.com
925.485.4527
headquarters: USA
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