Anti-MIP-3 alpha Antibody Biotin Conjugated | Boster B00748 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-MIP-3 alpha Antibody Biotin Conjugated

catalog :

B00748

quantity :

100 ug

price :

329 USD

clonality :

polyclonal

host :

rabbit

conjugate :

biotin

reactivity :

human, mouse

application :

western blot, immunohistochemistry

product information

sku :

B00748

name :

Anti-MIP-3 alpha Antibody Biotin Conjugated

price :

329 USD

form :

Lyophilized

host :

Rabbit

clonality :

Polyclonal

description :

Anti-MIP-3 alpha Antibody Biotin Conjugated validated for WB in Human.

size :

100 ug

reactivity :

Human

applications :

IHC; WB

background :

Macrophage Inflammatory Protein 3alpha(MIP3alpha), also called Chemokine, cc motif, ligand 20(CCL20). The MIP-3alpha/CCL20 gene was cloned and sequenced, revealing a four exon, three intron structure, and was localized by FISH analysis to 2q35-q36. MIP3alpha is predominantly expressed in lymph nodes, appendix, PBL, fetal liver, fetal lung and several cell lines. MIP3alpha/CCL20 and its receptor CCR6 are markedly up-regulated in psoriasis, and they may play a role in the recruitment of T cells to lesional psoriatic skin. And Alanine MIP-3alpha and Serine MIP-3alpha, the two forms of MIP3alpha, that differ by one amino acid at the predicted signal peptide cleavage site. Both of them were chemically synthesized and tested for biological activity. And both flu antigen plus IL-2-activated CD4(+) and CD8(+) T lymphoblasts and cord blood-derived dendritic cells responded to Ser and Ala MIP-3alpha.

concentration :

1.0 mg/mL by UV absorbance at 280 nm

conjugate :

Biotin

gene full name :

C-C motif chemokine 20

gene name :

Ccl20

protein function :

Chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells.

research category :

immunology innate immunity macrophage / inflamm. immunology chemokines beta chemokines (cc) signal transduction signaling pathway g protein signaling gpcr kits/ lysates/ other elisa kits cytokines and cytokine receptors elisa kits

subcellular localization :

Secreted.

synonyms :

C-C motif chemokine 20;Beta-chemokine exodus-1;CC chemokine LARC;CC chemokine ST38;Liver and activation-regulated chemokine;Macrophage inflammatory protein 3 alpha;MIP-3-alpha;Small-inducible cytokine A20;Ccl20;Larc, Scya20;

tissue specificity :

Prominently expressed in the small intestine, colon and appendix. Also found in thymus, spleen, lymph node and lung. The long form might be dominant in intestinal, and the short form in lymphoid tissues.

uniprot id :

O89093