Anti-Fibronectin FN1 Antibody Biotin Conjugated | Boster B00564 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-Fibronectin FN1 Antibody Biotin Conjugated

catalog :

B00564

quantity :

100 ug

clonality :

polyclonal

host :

domestic rabbit

conjugate :

biotin

clone name :

polyclonal

reactivity :

human

application :

immunohistochemistry, immunoprecipitation

product information

SKU :

B00564

Product Name :

Anti-Fibronectin FN1 Antibody Biotin Conjugated

Size :

100 ug

Clonality :

Polyclonal

Host :

Rabbit

Conjugate :

Biotin

Reactivity :

Human

Predicted Reactivity :

Bovine, Monkey

Application(s) :

IP, IHC

Application Details :

ImmunoPrecipitation: 1:100, human, mouse, rat, bovine, monkeyImmunohistochemistry: 1:50 - 1:200, human, mouse, rat, bovine, monkey

Description :

Boster Bio Anti-Fibronectin FN1 Antibody Biotin Conjugated catalog # B00564. Tested in IP, IHC applications. This antibody reacts with Human.

Concentration :

1.0 mg/mL by UV absorbance at 280 nm

Gene Name :

FN1

Uniprot ID :

P02751

Form :

Lyophilized

Cross-reactivity :

No cross reactivity with other proteins.

Gene Full Name :

Fibronectin

Synonyms :

Fibronectin; FN; Cold-insoluble globulin; CIG; Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3; FN1; FN;

Molecular Weight :

262625 MW

Protein Function :

Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts.

Subcellular Localization :

Secreted, extracellular space, extracellular matrix.

Tissue Specificity :

Plasma FN (soluble dimeric form) is secreted by hepatocytes. Cellular FN (dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix. Ugl-Y1, Ugl-Y2 and Ugl-Y3 are found in urine.

Background :

Fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. Cellular fibronectin is a 550KDa glycoprotein existing as two heterodimers, different from plasma fibronectin in the presence of additional polypeptide segments and in altering morphology of transformed cells and hemaglutination.