Anti-COLLAGEN Type I COL1A1 Antibody Biotin Conjugated

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-COLLAGEN Type I COL1A1 Antibody Biotin Conjugated

catalog :

B00329

quantity :

100 ug

clonality :

polyclonal

host :

domestic rabbit

conjugate :

biotin

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunoprecipitation, flow cytometry

product information

SKU :

B00329

Product Name :

Anti-COLLAGEN Type I COL1A1 Antibody Biotin Conjugated

Size :

100 ug

Clonality :

Polyclonal

Host :

Rabbit

Conjugate :

Biotin

Reactivity :

Human, Mouse, Rat

Predicted Reactivity :

Bovine

Application(s) :

WB, IP, IHC, Flow Cytometry

Application Details :

Western Blot, 1:3, 000 - 1:6, 000, human, mouse, rat, bovine.ImmunoPrecipitation, 1:100, human, mouse, rat, bovineImmunohistochemistry, 1:50 - 1:200, human, mouse, rat, bovine

Description :

Boster Bio Anti-COLLAGEN Type I COL1A1 Antibody Biotin Conjugated catalog # B00329. Tested in Flow Cytometry, IP, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

1.0 mg/mL by UV absorbance at 280 nm

Gene Name :

COL1A1

Uniprot ID :

P02452

Immunogen :

Collagen Type I from human and bovine placenta.

Form :

Lyophilized

Contents :

0.125 M Sodium Borate. 0.075 M Sodium Chloride. 0.005 M EDTA. pH 8.0. 0.01% (w/v) Sodium Azide

Cross-reactivity :

No cross reactivity with other proteins.

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Collagen alpha-1(I) chain

Synonyms :

Collagen alpha-1 (I) chain; Alpha-1 type I collagen; COL1A1;

Molecular Weight :

138941 MW

Protein Function :

Type I collagen is a member of group I collagen (fibrillar forming collagen).

Subcellular Localization :

Secreted, extracellular space, extracellular matrix.

Tissue Specificity :

Forms the fibrils of tendon, ligaments and bones. In bones the fibrils are mineralized with calcium hydroxyapatite.

Background :

Collagen, type I, alpha 1, also known as COL1A1, is a human gene that encodes the major component of type I collagen, the fibrillar collagen found in most connective tissues, including cartilage. This gene is mapped to 17q21.33. This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis.

Research Category :

Collagen, Cytoskeleton / Ecm, Ecm Proteins, Extracellular Matrix, Mesenchymal Stem Cells, Signal Transduction, Stem Cells