Anti-IL-4 Antibody Biotin Conjugated | Boster B00230 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-IL-4 Antibody Biotin Conjugated

catalog :

B00230

quantity :

100 ug

price :

329 USD

clonality :

polyclonal

host :

rabbit

conjugate :

biotin

reactivity :

human

application :

western blot, immunohistochemistry

product information

sku :

B00230

name :

Anti-IL-4 Antibody Biotin Conjugated

price :

329 USD

form :

Lyophilized

host :

Rabbit

clonality :

Polyclonal

description :

Anti-IL-4 Antibody Biotin Conjugated validated for WB in Human.

size :

100 ug

reactivity :

Human

applications :

IHC; WB

background :

Interleukin-4(IL-4), also knowns as a B-cell stimulatory factor1(BSF1), is an immunomodulatory cytokine, which can inhibit the growth of tumour cells.The human cDNA contains a single open reading frame encoding a protein of 153 amino acids, including a putative signal peptide. IL-4 may act as an autocrine growth factor in pancreatic cancer cells and also give rise to the possibility that cancer-derived IL-4 may suppress cancer-directed immunosurveillance in vivo in addition to its growth-promoting effects, thereby facilitating pancreatic tumor growth and metastasis. The mouse and human genes and their protein products show structural and functional similarities. The human IL-4 gene, which occurs as a single copy in the haploid genome, is mapped on chromosome 5. The standard product used in this kit is recombinant human IL-4, consisting of 130 amino acids with the molecular mass of 14KDa.

concentration :

0.80 mg/ml by UV absorbance at 280 nm

conjugate :

Biotin

gene full name :

Interleukin-4

gene name :

IL4

protein function :

Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.

research category :

immunology innate immunity cytokines interleukins cancer tumor immunology immunology adaptive immunity regulatory t cells

subcellular localization :

Secreted .

synonyms :

Interleukin-4 ;IL-4 ;B-cell stimulatory factor 1 ;Lymphocyte stimulatory factor 1 ;IL4 ;hCG_24113 ;

uniprot id :

D4HNR6