Anti-IL-1 beta Antibody Biotin Conjugated | Boster B00101 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-IL-1 beta Antibody Biotin Conjugated

catalog :

B00101

quantity :

100 ug

price :

329 USD

clonality :

polyclonal

host :

rabbit

conjugate :

biotin

reactivity :

human

application :

western blot, immunohistochemistry

product information

sku :

B00101

name :

Anti-IL-1 beta Antibody Biotin Conjugated

price :

329 USD

form :

Lyophilized

host :

Rabbit

clonality :

Polyclonal

description :

Anti-IL-1 beta Antibody Biotin Conjugated validated for WB in Human.

size :

100 ug

reactivity :

Human

applications :

IHC; WB

background :

The Interleukin 1 family is a group of 11 beta trefoil cytokines. Interleukin-1, produced mainly by blood monocytes, mediates the panoply of host reactions collectively known as acute phase response . Interleukin-1beta(IL-1beta) is a potent stimulator of bone resorption, and has been implicated in the pathogenesis of high bone turnover and osteoporosis. IL-1beta belongs to proinflammatory cytokines, promote cancer cell adhesion and liver metastases by up-regulating the expression of vascular cell adhesion molecule-1(VCAM-1) on hepatic sinusoidal endothelium(HSE).

concentration :

1.0 mg/mL by UV absorbance at 280 nm

conjugate :

Biotin

cross reactivity :

No cross reactivity with other proteins.

gene full name :

Interleukin-1 beta

gene name :

IL1B

predicted reactivity :

Canine; Primate

protein function :

Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.

subcellular localization :

Secreted. The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.

synonyms :

Interleukin-1 beta;IL-1 beta;Catabolin;IL1B;IL1F2;

uniprot id :

P01584