Anti-Transferrin Antibody Biotin Conjugated | Boster B00094 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-Transferrin Antibody Biotin Conjugated

catalog :

B00094

quantity :

100 uL

price :

95 USD

clonality :

polyclonal

host :

rabbit

conjugate :

biotin

reactivity :

human

application :

western blot, immunohistochemistry

product information

sku :

B00094

name :

Anti-Transferrin Antibody Biotin Conjugated

price :

95 USD

form :

Liquid

host :

Rabbit

clonality :

Polyclonal

description :

Anti-Transferrin Antibody Biotin Conjugated validated for WB in Human.

size :

100 uL

reactivity :

Human

applications :

IHC; WB

background :

Transferrins are iron-binding blood plasma glycoproteins that control the level of free iron in biological fluids. In humans, it is encoded by the TF gene. Transferrin consists of a polypeptide chain containing 679 amino acids in humans. The protein is composed of alpha helices and beta sheets to form two domains. The N- and C- terminal sequences are represented by globular lobes and between the two lobes is an iron-binding site. Transferrin is a glycoprotein that binds iron very tightly but reversibly. Although iron bound to transferrin is less than 0.1% (4 mg) of the total body iron, it is the most important iron pool, with the highest rate of turnover (25 mg/24 h). And Transferrin has a molecular weight of around 80 kDa and contains 2 specific high-affinity Fe(III) binding sites. The affinity of transferrin for Fe(III) is extremely high (1023 M???1 at pH 7.4) but decreases progressively with decreasing pH below neutrality.

concentration :

1.0 mg/mL by UV absorbance at 280 nm

conjugate :

Biotin

gene full name :

Serotransferrin

gene name :

protein function :

Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.

research category :

tags & cell markers cell type markers tumor associated epigenetics and nuclear signaling transcription domain families hlh / leucine zipper transcription factors chip'ing antibodies

subcellular localization :

Secreted.

synonyms :

Serotransferrin;Transferrin;Beta-1 metal-binding globulin;Siderophilin;TF;PRO1400;

tissue specificity :

Expressed by the liver and secreted in plasma.

uniprot id :

P02787