Anti-ICK Antibody | Boster A06270 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-ICK Antibody

catalog :

A06270

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

immunohistochemistry, immunocytochemistry

product information

sku :

A06270

status :

Enabled

name :

Anti-ICK Antibody

category name :

Primary Antibodies, Polyclonal Antibodies, IHC ICC IF Antibodies

gene name :

ICK

price various sizes :

5ul sample size / $40 100ul / $299 100ul+Free HRP Secondary BA1054 / $299 100ul+Free Biotin Secondary BA1003 / $299

clonality :

Polyclonal

concentration :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

conjugate :

contents :

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

description :

Polyclonal antibody for ICK detection. Host: Rabbit.Size: 100ul. Tested applications: IF. Reactive species: Human. ICK information: Molecular Weight: 71427 MW; Subcellular Localization: Nucleus . Cytoplasm, cytosol . Cell projection, cilium . Cytoplasm, cytoskeleton, cilium basal body . Also found at the ciliary tip (PubMed:24797473). Nuclear localization has been observed with a GFP-tagged construct in transfected HeLa cells (PubMed:12103360); Tissue Specificity: Expressed in heart, brain, placenta, pancreas, thymus, prostate, testis, ovary, small intestine and colon, with highest levels in placenta and testis. Not detected in spleen. Also expressed in many cancer cell lines.

short description :

Rabbit Polyclonal Antibody for ICK (ICK) detection. Tested with IHC, IF in Human, Mouse.

size :

100 ul

sample size available :

5ul, free with shipping charge

uniprot id :

Q9UPZ9

host :

Rabbit

immunogen :

Synthesized peptide derived from internal of human ICK.

form :

Liquid

purification :

Immunogen affinity purified

storage :

Store at -20 C for one year, at 4 C for one month. We suggest the antibody be aliquotted into small vials and stored frozen at -20 C upon receiving. Avoid repeated freezing and thawing.

application details :

IHC, 1:50-1:100. Immunofluorescence, 1:100-1:500.

applications :

IF, IHC

reactivity :

Human, Mouse

image labels :

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using ICK antibody A06270. Immunofluorescence analysis of HeLa cells, using ICK antibody A06270.

competitor equivalent skus :

sc 134510 sc 365244 sc 48020

research category :

Cell Biology, Cell Cycle, Epigenetics And Nuclear Signaling, Kinases/Phosphatases

synonyms :

Serine/threonine-protein kinase ICK;2.7.11.22;Intestinal cell kinase;hICK;Laryngeal cancer kinase 2;LCK2;MAK-related kinase;MRK;ICK;KIAA0936;

gene full name :

Serine/threonine-protein kinase ICK

molecular weight :

71427 MW

protein function :

Required for ciliogenesis (PubMed:24797473). Phosphorylates KIF3A (By similarity). Involved in the control of ciliary length (PubMed:24853502). Regulates the ciliary localization of SHH pathway components as well as the localization of IFT components at ciliary tips (By similarity). May play a key role in the development of multiple organ systems and particularly in cardiac development (By similarity). Regulates intraflagellar transport (IFT) speed and negatively regulates cilium length in a cAMP and mTORC1 signaling-dependent manner and this regulation requires its kinase activity (By similarity).

subcellular localization :

Nucleus . Cytoplasm, cytosol . Cell projection, cilium . Cytoplasm, cytoskeleton, cilium basal body . Also found at the ciliary tip (PubMed:24797473). Nuclear localization has been observed with a GFP-tagged construct in transfected HeLa cells (PubMed:12103360).

tissue specificity :

Expressed in heart, brain, placenta, pancreas, thymus, prostate, testis, ovary, small intestine and colon, with highest levels in placenta and testis. Not detected in spleen. Also expressed in many cancer cell lines.

last modified :

2/6/19 22:57