Anti-IL-37 Antibody | Boster A03607 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-IL-37 Antibody

catalog :

A03607

quantity :

100 ug

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot

product information

sku :

A03607

status :

Enabled

name :

Anti-IL-37 Antibody

category name :

Primary Antibodies, Polyclonal Antibodies

gene name :

IL37

price various sizes :

25ug sample size / $99 25ug sample size / $99 100 ug / $299 100 ug / $299 100 ug+Free HRP Secondary BA1054 / $299 100 ug+Free Biotin Secondary BA1054 / $299 100 ug+Free Biotin Secondary BA1003 / $299 100 ug+Free Biotin Secondary BA1003 / $299

clonality :

Polyclonal

concentration :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

conjugate :

contents :

100 ug in 200 ul PBS containing 0.05% BSA and 0.05% sodium azide.

description :

Polyclonal antibody for IL 1F7/IL37 detection. Host: Rabbit.Size: 100 ug. Tested applications: WB. Reactive species: Human. IL 1F7/IL37 information: Molecular Weight: 24126 MW; Subcellular Localization: Cytoplasm, cytosol. Nucleus. Secreted. Stimulation with IL1B leads to colocalization with SMAD3 mostly in perinuclear regions. Only the CASP1-cleaved mature form translocates into the nucleus upon LPS stimulation; Tissue Specificity: In general, low constitutive expression, if any, in healthy tissues; high expression in inflammatory counterparts, including in synovial tissues from individuals with active rheumatoid arthritis. Isoform A, isoform B and isoform C are expressed in testis, colon, placenta, lung and lymph node. Isoform D and isoform E were found only in testis and bone marrow. Whereas only isoform A is found in brain, only isoform B in kidney and only isoform C in heart.

short description :

Rabbit IgG Polyclonal antibody for IL37 detection. Tested with WB in Human.

size :

100 ug

sample size available :

25ug for $99, contact us for details

uniprot id :

Q9NZH6

host :

Rabbit

immunogen :

Full length recombinant IL-37 protein.

form :

Liquid

storage :

Store the antibody at 4 C, stable for 6 months. For long-term storage, store at -20 C. Avoid repeated freeze and thaw cycles.

application details :

Western blot analysis, 2-4 ug/ml.

applications :

reactivity :

Human

image labels :

Western blot analysis of IL-37. Anti- IL-37 antibody was used at 2 ug/ml on (1) A549 and (2) HCT-116 lysates.

competitor equivalent skus :

sc 168153 sc 168152

research category :

Cytokines, Immunology, Innate Immunity, Interleukins, Macrophage / Inflamm.

synonyms :

Interleukin-37;FIL1 zeta;IL-1X;Interleukin-1 family member 7;IL-1F7;Interleukin-1 homolog 4;IL-1H;IL-1H4;Interleukin-1 zeta;IL-1 zeta;Interleukin-1-related protein;IL-1RP1;Interleukin-23;IL-37;IL37;FIL1Z, IL1F7, IL1H4, IL1RP1;

gene full name :

Interleukin-37

molecular weight :

24126 MW

protein function :

Suppressor of innate inflammatory and immune responses involved in curbing excessive inflammation. This function requires SMAD3. Suppresses, or reduces, proinflammatory cytokine production, including IL1A and IL6, as well as CCL12, CSF1, CSF2, CXCL13, IL1B, IL23A and IL1RN, but spares anti-inflammatory cytokines. Inhibits dendritic cell activation.

subcellular localization :

Cytoplasm, cytosol. Nucleus. Secreted. Stimulation with IL1B leads to colocalization with SMAD3 mostly in perinuclear regions. Only the CASP1-cleaved mature form translocates into the nucleus upon LPS stimulation.

tissue specificity :

In general, low constitutive expression, if any, in healthy tissues; high expression in inflammatory counterparts, including in synovial tissues from individuals with active rheumatoid arthritis. Isoform A, isoform B and isoform C are expressed in testis, colon, placenta, lung and lymph node. Isoform D and isoform E were found only in testis and bone marrow. Whereas only isoform A is found in brain, only isoform B in kidney and only isoform C in heart.

protein name :

Interleukin-37

last modified :

2/6/19 22:57