Anti-NT-3 NTF3 Antibody | Boster A03348-1 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-NT-3 NTF3 Antibody

catalog :

A03348-1

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

polyclonal

reactivity :

human

application :

immunohistochemistry, flow cytometry

product information

SKU :

A03348-1

Product Name :

Anti-NT-3 NTF3 Antibody

Size :

100 ul

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Application(s) :

IHC, ELISA, Flow Cytometry

Application Details :

IHC-P 1:50-300 ELISA 1:5000-20000

Description :

Boster Bio Anti-NT-3 NTF3 Antibody catalog # A03348-1. Tested in ELISA, Flow Cytometry, IHC applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

1 mg/ml

Gene Name :

NTF3

Uniprot ID :

P20783

Immunogen :

Synthetic peptide from human NT-3 protein.

Form :

Liquid

Contents :

PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

Purification :

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Isotype :

IgG

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

C-X-C chemokine receptor type 4

Synonyms :

C-X-C chemokine receptor type 4; CXC-R4; CXCR-4; FB22; Fusin; HM89; LCR1; Leukocyte-derived seven transmembrane domain receptor; LESTR

Protein Name :

C-X-C chemokine receptor type 4

Molecular Weight :

39746 MW

Protein Function :

Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation (PubMed:10452968, PubMed:28978524, PubMed:18799424, PubMed:24912431). Involved in the AKT signaling cascade (PubMed:24912431). Plays a role in regulation of cell migration, e.g. during wound healing (PubMed:28978524). Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels (PubMed:20228059). Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes (PubMed:11276205). Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal- neuron survival (By similarity).

Subcellular Localization :

Cell membrane

Tissue Specificity :

Expressed in numerous tissues, such as peripheral blood leukocytes, spleen, thymus, spinal cord, heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, cerebellum, cerebral cortex and medulla (in microglia as well as in astrocytes), brain microvascular, coronary artery and umbilical cord endothelial cells. Isoform 1 is predominant in all tissues tested.