Anti-IL1R2 Antibody | Boster A03106 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-IL1R2 Antibody

catalog :

A03106

quantity :

100 ug/200 ul

price :

290 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot

product information

sku :

A03106

name :

Anti-IL1R2 Antibody

price :

290 USD

immunogen :

Synthetic peptide with sequence C-QYNITRSIELRIKK, corresponding to the internal region of the protein sequence.

form :

Liquid

host :

Goat

contents :

Each vial contains the specific antibody at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% BSA.

purification :

Immunogen Affinity Purified

clonality :

Polyclonal

description :

Goat Anti-IL1R2 Antibody for IL1R2 detection tested with WB in Human.

size :

100 ug/200 ul

reactivity :

Human

applications :

background :

Interleukin 1 receptor, type II(IL1R2) also known as CD121b(Cluster of Differentiation 121b) is an interleukin receptor. The protein encoded by this gene is a cytokine receptor that belongs to the interleukin-1 receptor family. It is mapped to 2q11.2. IL1R2 binds interleukin alpha(IL1A), interleukin beta(IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. IL1R2 also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. The secreted IL1R2 recruits secreted IL1RAP with high affinity, and this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.

concentration :

85 mg/mL by Refractometry

cross reactivity :

No cross reactivity with other proteins.

gene full name :

Interleukin-1 receptor type 2

gene name :

IL1R2

predicted reactivity :

Primate

protein function :

Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.

research category :

immunology innate immunity cytokines interleukins stem cells hematopoietic progenitors lymphoid b lymphocytic lineage

storage :

At -20 for one year. After reconstitution, at 4 for one month. It can also be aliquotted and stored frozen at -20 for a longer time. Avoid repeated freezing and thawing.

subcellular localization :

Isoform Short: Secreted .

synonyms :

Interleukin-1 receptor type 2;IL-1R-2;IL-1RT-2;IL-1RT2;CD121 antigen-like family member B;CDw121b;IL-1 type II receptor;Interleukin-1 receptor beta;IL-1R-beta;Interleukin-1 receptor type II;CD121b;Interleukin-1 receptor type 2, membrane form;mIL-1R2;mIL-1RII;Interleukin-1 receptor type 2, soluble form;sIL-1R2;sIL-1RII;IL1R2;IL1RB;

uniprot id :

P27930