Anti-Caspase-6/CASP6 Antibody Picoband™ | Boster A02631 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Caspase-6/CASP6 Antibody Picoband™

catalog :

A02631

quantity :

100 ug/vial

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot

product information

SKU :

A02631

Product Name :

Anti-Caspase-6/CASP6 Antibody Picoband™

Size :

100 ug/vial

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Application(s) :

Application Details :

Western blot, 0.1-0.5µg/ml, Mouse, Rat, Human.

Application Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-Caspase-6/CASP6 Antibody Picoband™ catalog # A02631. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Gene Name :

CASP6

Uniprot ID :

P55212

Immunogen :

E. coli-derived human Caspase-6 recombinant protein (Position: A194-N293). Human Caspase-6 shares 95.9% and 93.9% amino acid (aa) sequence identity with mouse and rat Caspase-6, respectively.

Form :

Lyophilized

Contents :

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Purification :

Immunogen affinity purified.

Cross-reactivity :

No cross reactivity with other proteins.

Storage :

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Gene Full Name :

Caspase-6

Synonyms :

Caspase-6; CASP-6; 3.4.22.59; Apoptotic protease Mch-2; Caspase-6 subunit p18; Caspase-6 subunit p11; CASP6; MCH2;

Molecular Weight :

33310 MW

Protein Function :

Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly (ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.

Subcellular Localization :

Cytoplasm

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.

Background :

Caspase 6 is an enzyme that in humans is encoded by the CASP6 gene. This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Using radiation hybrid mapping, the CASP6 gene is localized to human chromosome 4q25-q26. It functions as a downstream enzyme in the caspase activation cascade. And CASP6 can cleave lamin A to its signature apoptotic fragment.

Research Category :

Metabolism, Metabolism Processes, Neurodegenerative Disease, Neurology Process, Neuroscience, Pathways And Processes